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F9 coagulation factor IX [ Sus scrofa (pig) ]

Gene ID: 397518, updated on 6-May-2021

Summary

Gene symbol
F9
Gene description
coagulation factor IX
See related
Ensembl:ENSSSCG00000012711
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
FIXA
Expression
Biased expression in liver (RPKM 227.9), mixtures (RPKM 90.2) and 1 other tissue See more
Orthologs
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Genomic context

Location:
chromosome: X
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (114218704..114250436)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (130417620..130448319)

Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor 13 Neighboring gene uncharacterized LOC110257819 Neighboring gene uncharacterized LOC110257820 Neighboring gene 40S ribosomal protein S27-like Neighboring gene MCF.2 cell line derived transforming sequence Neighboring gene ATPase phospholipid transporting 11C Neighboring gene microRNA mir-505

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables endopeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in blood coagulation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in proteolysis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in zymogen activation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
coagulation factor IX
Names
christmas factor
NP_001157475.1
XP_020935171.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164003.1NP_001157475.1  coagulation factor IX

    Status: PROVISIONAL

    Source sequence(s)
    AK232625
    UniProtKB/TrEMBL
    F1RQ75
    Related
    ENSSSCP00000013514.3, ENSSSCT00000013897.4
    Conserved Domains (5) summary
    smart00020
    Location:227455
    Tryp_SPc; Trypsin-like serine protease
    smart00069
    Location:2892
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:93129
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:228458
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam14670
    Location:134170
    FXa_inhibition; Coagulation Factor Xa inhibitory site

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

    Range
    114218704..114250436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021079512.1XP_020935171.1  coagulation factor IX isoform X1

    Related
    ENSSSCP00000055678.1, ENSSSCT00000044683.2
    Conserved Domains (3) summary
    smart00069
    Location:2892
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:93129
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:185415
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
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