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ATPsynbetaL ATP synthase, beta subunit-like [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39761, updated on 10-May-2024

Summary

Official Symbol
ATPsynbetaLprovided by FlyBase
Official Full Name
ATP synthase, beta subunit-likeprovided by FlyBase
Primary source
FLYBASE:FBgn0036568
Locus tag
Dmel_CG5389
See related
AllianceGenome:FB:FBgn0036568
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
ATPB; ATPsyn-betalike; CG5389; Dmel\CG5389; ms(3)72Dt
Summary
Predicted to enable ATP binding activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Involved in determination of adult lifespan; regulation of proton transport; and spermatid differentiation. Predicted to be part of mitochondrial proton-transporting ATP synthase, catalytic core. Is expressed in adult head; organism; and spermatozoon. Orthologous to human ATP5F1B (ATP synthase F1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See ATPsynbetaL in Genome Data Viewer
Location:
72D5-72D6; 3-44 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16097834..16100088)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16090934..16093188)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Chloride channel-c Neighboring gene uncharacterized protein Neighboring gene Isoleucyl-tRNA synthetase, mitochondrial Neighboring gene Integrator 9 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
 
enables proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
 
contributes_to proton-transporting ATP synthase activity, rotational mechanism ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in ATP metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
 
involved_in proton motive force-driven ATP synthesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in proton motive force-driven mitochondrial ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of proton transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatid differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of mitochondrial proton-transporting ATP synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial proton-transporting ATP synthase, catalytic core ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of proton-transporting ATP synthase complex, catalytic core F(1) IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of proton-transporting ATP synthase complex, catalytic core F(1) IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATP synthase, beta subunit-like
Names
ATP synthase beta chain
ATPsynbetaL-PA
CG5389-PA
male sterile (3) 72Dt

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16097834..16100088
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140579.2NP_648836.2  ATP synthase, beta subunit-like [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648836.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T4C4, Q9VUY3
    Related
    FBpp0075203
    Conserved Domains (4) summary
    PRK09280
    Location:103568
    PRK09280; F0F1 ATP synthase subunit beta; Validated
    cd01133
    Location:175454
    F1-ATPase_beta; F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a ...
    pfam00306
    Location:462571
    ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
    pfam02874
    Location:106173
    ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain