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gtf3a.L general transcription factor 3A L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397777, updated on 6-Oct-2023

Summary

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Official Symbol
gtf3a.L
Official Full Name
general transcription factor 3A L homeolog
Primary source
Xenbase:XB-GENE-6252591
Locus tag
XELAEV_18013758mg
See related
EnsemblRapid:ENSXLAG00005000694
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gtf3a; TFIIIA
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Genomic context

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Location:
chromosome: 2L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (164963144..164974006, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (159062042..159072905, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene RNA polymerase I and III subunit D, gene 1 L homeolog Neighboring gene ligand of numb-protein X 2 L homeolog Neighboring gene phosphatidylinositol polyphosphate 5-phosphatase type IV-like Neighboring gene phosphatidylinositol polyphosphate 5-phosphatase type IV-like Neighboring gene probable serine/threonine-protein kinase mkcA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Side projections of double-helical DNA: example of binding patterns of DNA in the complex with factor TFIIIA. Chirgadze YN, et al. J Biomol Struct Dyn, 2019 Oct. PMID 30513263
  2. Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA. Lee BM, et al. J Mol Biol, 2006 Mar 17. PMID 16405997
  3. Is there a dynamic DNA-protein interface in the transcription factor IIIA-5 S rRNA gene complex? Brady KL, et al. J Biol Chem, 2005 Apr 22. PMID 15713659
  4. Binding of zinc finger protein transcription factor IIIA to its cognate DNA sequence with single UV photoproducts at specific sites and its effect on DNA repair. Kwon Y, et al. J Biol Chem, 2003 Nov 14. PMID 12963720
  5. Phosphorylation of Xenopus transcription factor IIIA by an oocyte protein kinase CK2. Westmark CJ, et al. Biochem J, 2002 Mar 1. PMID 11853545, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the views of the binding patterns of operator DNA in complex with transcription factor TFIIIA from X. laevis, are presented.
    Title: Side projections of double-helical DNA: example of binding patterns of DNA in the complex with factor TFIIIA.
  2. transcription factor IIIA binding to DNA is affected by single UV photoproducts
    Title: Binding of zinc finger protein transcription factor IIIA to its cognate DNA sequence with single UV photoproducts at specific sites and its effect on DNA repair.
  3. rapid movements of side chains permit them to make fluctuating contacts with adjacent bp in the DNA of the 5S rRNA gene
    Title: Is there a dynamic DNA-protein interface in the transcription factor IIIA-5 S rRNA gene complex?
  4. Results describe the solution structure of the middle three zinc fingers of transcription factor IIIA bound to the central core of 5S RNA.
    Title: Induced fit and "lock and key" recognition of 5S RNA by zinc fingers of transcription factor IIIA.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ribosomal large subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription factor IIIA
Names
S-TFIIIA/O-TFIIIA
factor A
general transcription factor IIIA

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087859.1 → NP_001081328.1  transcription factor IIIA

    See identical proteins and their annotated locations for NP_001081328.1

    Status: PROVISIONAL

    Source sequence(s)
    K02938
    UniProtKB/TrEMBL
    A2VD71
    Related
    ENSXLAP00005002004.1, ENSXLAT00005002050.1
    Conserved Domains (2) summary
    COG5048
    Location:37 → 159
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:19 → 37
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    164963144..164974006 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P03001.2 GenPept UniProtKB/Swiss-Prot:P03001

Gene LinkOut

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