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MIR1915HG MIR1915 host gene [ Homo sapiens (human) ]

Gene ID: 399726, updated on 5-Mar-2024

Summary

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Official Symbol
MIR1915HGprovided by HGNC
Official Full Name
MIR1915 host geneprovided by HGNC
Primary source
HGNC:HGNC:31448
See related
Ensembl:ENSG00000204682 AllianceGenome:HGNC:31448
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CASC10; C10orf114; bA418C1.3
Expression
Broad expression in kidney (RPKM 3.7), liver (RPKM 3.6) and 15 other tissues See more
Orthologs
all
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Genomic context

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Location:
10p12.31
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (21492658..21497260, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (21511792..21516394, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (21781587..21786189, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376445 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:21706197-21706710 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21760456-21760650 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:21761953-21762749 Neighboring gene uncharacterized LOC124902598 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21783452-21784245 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2187 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2188 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21793394-21793626 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2189 Neighboring gene microRNA 1915 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814003-21814646 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814647-21815290 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2191 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2192 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21816390-21816548 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:21817867-21818510 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21822730-21823443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2196 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2197 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:21824159-21824871 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21825135-21825648 Neighboring gene SKI/DACH domain containing 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21840002-21840186 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21844418-21845000 Neighboring gene MLLT10 histone lysine methyltransferase DOT1L cofactor Neighboring gene RNA, U6 small nuclear 306, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Common variation at 10p12.31 near MLLT10 influences meningioma risk. Dobbins SE, et al. Nat Genet, 2011 Jul 31. PMID 21804547, Free PMC Article
  2. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054
  3. High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. Uren PJ, et al. RNA Biol, 2016. PMID 26760575, Free PMC Article
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. Abdelmohsen K, et al. EMBO J, 2009 May 6. PMID 19322201, Free PMC Article
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Other Names

  • cancer susceptibility 10
  • cancer susceptibility candidate 10
  • cancer susceptibility candidate gene 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_160800.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL358780
    Related
    ENST00000658000.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    21492658..21497260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    21511792..21516394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001010911.3: Suppressed sequence

    Description
    NM_001010911.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5T4H9.1 GenPept UniProtKB/Swiss-Prot:Q5T4H9

Gene LinkOut

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