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PCBP1-AS1 PCBP1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 400960, updated on 6-Nov-2023

Summary

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Official Symbol
PCBP1-AS1provided by HGNC
Official Full Name
PCBP1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:42948
See related
Ensembl:ENSG00000179818 AllianceGenome:HGNC:42948
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Linc-GALH
Expression
Ubiquitous expression in testis (RPKM 3.5), ovary (RPKM 2.9) and 24 other tissues See more
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Genomic context

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See PCBP1-AS1 in Genome Data Viewer
Location:
2p13.3
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (69962263..70088208, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (69973985..70099932, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (70189395..70314147, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11602 Neighboring gene Sharpr-MPRA regulatory region 10436 Neighboring gene MAX dimerization protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70164441-70164976 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:70173615-70174814 Neighboring gene aspartic peptidase retroviral like 1 Neighboring gene small nucleolar RNA U13 Neighboring gene Sharpr-MPRA regulatory region 1834 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70199285-70200162 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70202867-70203378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70203379-70203889 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70211622-70212122 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70212123-70212623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70220299-70220798 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:70224580-70224834 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15983 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:70256223-70257094 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15984 Neighboring gene Sharpr-MPRA regulatory region 12254 Neighboring gene RNA, 7SL, cytoplasmic 470, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15986 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15987 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15988 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11604 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70315031-70315675 Neighboring gene conserved acetylation island sequence C15 enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11605 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11606 Neighboring gene uncharacterized LOC124906022 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15989 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15990 Neighboring gene poly(rC) binding protein 1 Neighboring gene mitochondrial ribosomal protein L36 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression. Li Z, et al. Carcinogenesis, 2021 Jul 16. PMID 34107009
  2. The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin. Xu X, et al. Cell Death Dis, 2019 Jan 28. PMID 30692513, Free PMC Article
  3. lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma. Wang Q, et al. Aging (Albany NY), 2023 May 31. PMID 37256932, Free PMC Article
  4. Identification and evaluation of lncRNA and mRNA integrative modules in human peripheral blood mononuclear cells. Mo XB, et al. Epigenomics, 2017 Jul. PMID 28621149
  5. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. Navarini AA, et al. Nat Commun, 2014 Jun 13. PMID 24927181

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Association of LncRNA PCBP1-AS1 with cancer occurrence and development: A review.
    Title: Association of LncRNA PCBP1-AS1 with cancer occurrence and development: A review.
  2. LncRNA PCBP1-AS1 Induces Cerebral Ischemia/Reperfusion Injury via the miR-506-3p/CCL2 Axis.
    Title: LncRNA PCBP1-AS1 Induces Cerebral Ischemia/Reperfusion Injury via the miR-506-3p/CCL2 Axis.
  3. lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma.
    Title: lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma.
  4. LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression.
    Title: LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
EBI GWAS Catalog

Variation

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See Variation Viewer (GRCh37.p13)

General gene information

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Markers

Potential readthrough

Included gene: ASPRV1

Other Names

  • Gankyrin Associated LincRNA in Hepatocellular carcinoma
  • PCBP1 antisense RNA 1 (non-protein coding)

Clone Names

  • AC136007.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033872.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK308634, BC040598
    Related
    ENST00000435880.6

  2. NR_183088.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  3. NR_183089.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  4. NR_183090.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000684907.1

  5. NR_183091.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  6. NR_183092.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000653064.1

  7. NR_183093.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000657575.2

  8. NR_183094.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000702284.1

  9. NR_183095.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000659941.2

  10. NR_183096.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000661703.1

  11. NR_183097.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  12. NR_183098.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  13. NR_183099.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000669583.1

  14. NR_183100.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000668711.1

  15. NR_183101.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000654336.1

  16. NR_183102.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  17. NR_183103.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  18. NR_183104.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  19. NR_183105.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  20. NR_183106.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000653606.1

  21. NR_183107.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  22. NR_183108.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  23. NR_183109.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000653596.1

  24. NR_183110.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  25. NR_183111.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  26. NR_183112.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  27. NR_183113.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  28. NR_183114.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  29. NR_183115.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000666167.1

  30. NR_183116.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  31. NR_183117.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  32. NR_183118.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  33. NR_183119.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  34. NR_183120.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  35. NR_183121.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000655420.1

  36. NR_183122.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000666074.1

  37. NR_183123.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  38. NR_183124.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  39. NR_183125.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000655481.1

  40. NR_183126.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000702210.1

  41. NR_183127.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  42. NR_183129.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000416068.6

  43. NR_183130.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  44. NR_183131.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000612202.5

  45. NR_183132.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  46. NR_183133.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  47. NR_183134.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  48. NR_183135.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  49. NR_183136.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  50. NR_183137.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  51. NR_183138.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  52. NR_183139.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  53. NR_183140.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  54. NR_183141.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  55. NR_183142.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  56. NR_183143.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  57. NR_183144.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  58. NR_183145.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  59. NR_183146.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  60. NR_183147.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  61. NR_183148.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  62. NR_183150.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000654716.1

  63. NR_183151.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  64. NR_183152.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  65. NR_183153.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000664754.1

  66. NR_183154.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  67. NR_183155.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  68. NR_183156.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  69. NR_183157.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  70. NR_183158.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  71. NR_183159.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811
    Related
    ENST00000437019.2

  72. NR_183161.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  73. NR_183162.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  74. NR_183163.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  75. NR_183164.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  76. NR_183165.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  77. NR_183166.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  78. NR_183167.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  79. NR_183168.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  80. NR_183169.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  81. NR_183170.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  82. NR_183172.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

  83. NR_183173.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC016700, AC079811

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    69962263..70088208 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    69973985..70099932 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
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