ND-39 NADH dehydrogenase (ubiquinone) 39 kDa subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ND-39provided by FlyBase
Official Full Name: NADH dehydrogenase (ubiquinone) 39 kDa subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0037001
Locus tag: Dmel_CG6020
See related: AllianceGenome:FB:FBgn0037001
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG6020; Dmel\CG6020; dNDUFA9; GM13757p; Ndufa9; NDUFA9; NUEM
Summary: Predicted to enable catalytic activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly and ubiquinone-6 biosynthetic process. Predicted to be part of mitochondrial respiratory chain complex I. Predicted to be active in mitochondrion. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval muscle system; gastrula embryo; germ layer derivative; and visceral muscle primordium. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 26. Orthologous to human NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20492082..20497084)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (20485182..20490184)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein-containing complex binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IC Inferred by Curator more info	PubMed
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in ubiquinone-6 biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of mitochondrial respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

Names: CG6020-PA; CG6020-PB; FBpp0077859; NADH dehydrogenase; NADH ubiquinone oxidoreductase 39 kDa; NADH-ubiquinone oxidoreductase 39 kDa subunit; NADH:ubiquinone oxidoreductase 39 kDa subunit; ND-39-PA; ND-39-PB

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The following sections contain reference sequences that belong to a specific genome build. Explain