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hnrnph1 heterogeneous nuclear ribonucleoprotein H1 [ Danio rerio (zebrafish) ]

Gene ID: 402984, updated on 5-Jan-2022

Summary

Official Symbol
hnrnph1provided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein H1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1856
See related
Ensembl:ENSDARG00000040881
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:77712
Summary
Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Sjogren's syndrome and syndromic X-linked intellectual disability. Orthologous to several human genes including HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1). [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See hnrnph1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (6991176..7014588)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (6684452..6708154)
103 previous assembly Zv9 (GCF_000002035.4) 14 NC_007125.5 (6957484..6981407)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A/Ba Neighboring gene eukaryotic translation initiation factor 4E binding protein 3, like Neighboring gene RUN and FYVE domain containing 1 Neighboring gene heparin-binding EGF-like growth factor a Neighboring gene si:ch73-43g23.1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Homology

Clone Names

  • MGC77712

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein H; heterogeneous nuclear ribonucleoprotein H1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205684.1NP_991247.1  heterogeneous nuclear ribonucleoprotein H

    See identical proteins and their annotated locations for NP_991247.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065439
    UniProtKB/TrEMBL
    Q6P0V0
    Related
    ENSDARP00000059917.4, ENSDART00000059918.6
    Conserved Domains (4) summary
    COG0724
    Location:574
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12729
    Location:684
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:251326
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cl17169
    Location:89184
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    6991176..7014588
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169581.4XP_005169638.1  heterogeneous nuclear ribonucleoprotein H1 isoform X3

    Conserved Domains (4) summary
    COG0724
    Location:574
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12729
    Location:684
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:251326
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cl17169
    Location:89184
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. XM_005169579.4XP_005169636.1  heterogeneous nuclear ribonucleoprotein H1 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IZE3
    Related
    ENSDARP00000141886.1, ENSDART00000157635.2
    Conserved Domains (4) summary
    COG0724
    Location:574
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12729
    Location:684
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:251326
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cl17169
    Location:89184
    RRM_SF; RNA recognition motif (RRM) superfamily
  3. XM_021480996.1XP_021336671.1  heterogeneous nuclear ribonucleoprotein H1 isoform X4

    Conserved Domains (3) summary
    cd12729
    Location:684
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:251326
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cl17169
    Location:89184
    RRM_SF; RNA recognition motif (RRM) superfamily
  4. XM_005169580.4XP_005169637.1  heterogeneous nuclear ribonucleoprotein H1 isoform X2

    Conserved Domains (4) summary
    COG0724
    Location:574
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12729
    Location:684
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:251326
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cl17169
    Location:89184
    RRM_SF; RNA recognition motif (RRM) superfamily
  5. XM_005169582.4XP_005169639.1  heterogeneous nuclear ribonucleoprotein H1 isoform X5

    Conserved Domains (2) summary
    COG0724
    Location:88144
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
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