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CREM cAMP responsive element modulator [ Canis lupus familiaris (dog) ]

Gene ID: 403887, updated on 23-Dec-2021

Summary

Official Symbol
CREMprovided by VGNC
Official Full Name
cAMP responsive element modulatorprovided by VGNC
Primary source
VGNC:VGNC:52123
See related
Ensembl:ENSCAFG00845001664
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See CREM in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (2037957..2111330, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (1843669..1893973, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (1973934..2024249, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (1809553..1859860, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (1853133..1903529, complement)
105 previous assembly CanFam3.1 (GCF_000002285.3) 2 NC_006584.3 (1755189..1828746, complement)

Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene cyclin Y Neighboring gene uncharacterized LOC119870079 Neighboring gene 40S ribosomal protein S6-like Neighboring gene uncharacterized LOC111091150 Neighboring gene axin interactor, dorsalization-associated protein-like Neighboring gene protein SGT1 homolog Neighboring gene cullin 2

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cAMP-responsive element modulator
Names
cAMP responsive element moderator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003221.1NP_001003221.1  cAMP-responsive element modulator

    See identical proteins and their annotated locations for NP_001003221.1

    Status: PROVISIONAL

    Source sequence(s)
    X99115
    UniProtKB/Swiss-Prot
    P79145
    Conserved Domains (2) summary
    cd14690
    Location:288342
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:101138
    pKID; pKID domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051806.1 Reference ROS_Cfam_1.0

    Range
    2037957..2111330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038657747.1XP_038513675.1  cAMP-responsive element modulator isoform X19

    Conserved Domains (2) summary
    cd14690
    Location:180234
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  2. XM_038657745.1XP_038513673.1  cAMP-responsive element modulator isoform X17

    Conserved Domains (2) summary
    cd14690
    Location:192246
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  3. XM_038657740.1XP_038513668.1  cAMP-responsive element modulator isoform X13

    Conserved Domains (2) summary
    cd14690
    Location:229283
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  4. XM_038657739.1XP_038513667.1  cAMP-responsive element modulator isoform X12

    Conserved Domains (2) summary
    cd14690
    Location:241295
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  5. XM_038657737.1XP_038513665.1  cAMP-responsive element modulator isoform X10

    Conserved Domains (2) summary
    cd14690
    Location:243297
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  6. XM_038657729.1XP_038513657.1  cAMP-responsive element modulator isoform X3

    Conserved Domains (2) summary
    cd14690
    Location:292346
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  7. XM_038657734.1XP_038513662.1  cAMP-responsive element modulator isoform X7

    Conserved Domains (2) summary
    cd14690
    Location:255309
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  8. XM_038657731.1XP_038513659.1  cAMP-responsive element modulator isoform X5

    Conserved Domains (2) summary
    cd14690
    Location:288342
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:102138
    pKID; pKID domain
  9. XM_038657727.1XP_038513655.1  cAMP-responsive element modulator isoform X1

    Conserved Domains (2) summary
    cd14690
    Location:304358
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  10. XM_038657749.1XP_038513677.1  cAMP-responsive element modulator isoform X21

    Conserved Domains (2) summary
    cd14690
    Location:149203
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3874
    pKID; pKID domain
  11. XM_038657742.1XP_038513670.1  cAMP-responsive element modulator isoform X15

    Conserved Domains (2) summary
    cd14690
    Location:212266
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3874
    pKID; pKID domain
  12. XM_038657741.1XP_038513669.1  cAMP-responsive element modulator isoform X14

    Related
    ENSCAFP00845002619.1, ENSCAFT00845003302.1
    Conserved Domains (2) summary
    cd14690
    Location:224278
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:3874
    pKID; pKID domain
  13. XM_038657732.1XP_038513660.1  cAMP-responsive element modulator isoform X6

    Conserved Domains (2) summary
    cd14690
    Location:273327
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:87123
    pKID; pKID domain
  14. XM_038657736.1XP_038513664.1  cAMP-responsive element modulator isoform X9

    Conserved Domains (2) summary
    cd14690
    Location:249303
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:6399
    pKID; pKID domain
  15. XM_038657743.1XP_038513671.1  cAMP-responsive element modulator isoform X16

    Conserved Domains (2) summary
    cd14690
    Location:200254
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:1450
    pKID; pKID domain
  16. XM_038657752.1XP_038513680.1  cAMP-responsive element modulator isoform X24

    Conserved Domains (1) summary
    cd14690
    Location:57111
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  17. XM_038657750.1XP_038513678.1  cAMP-responsive element modulator isoform X22

    Conserved Domains (1) summary
    cd14690
    Location:69123
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  18. XM_038657757.1XP_038513685.1  cAMP-responsive element modulator isoform X28

    Conserved Domains (1) summary
    cd14690
    Location:3993
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  19. XM_038657754.1XP_038513682.1  cAMP-responsive element modulator isoform X26

    Conserved Domains (1) summary
    cd14690
    Location:46100
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  20. XM_038657756.1XP_038513684.1  cAMP-responsive element modulator isoform X27

    Conserved Domains (1) summary
    cd14690
    Location:46100
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  21. XM_038657728.1XP_038513656.1  cAMP-responsive element modulator isoform X2

    Related
    ENSCAFP00845002571.1, ENSCAFT00845003241.1
    Conserved Domains (2) summary
    cd14690
    Location:304358
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  22. XM_038657748.1XP_038513676.1  cAMP-responsive element modulator isoform X20

    Related
    ENSCAFP00845002581.1, ENSCAFT00845003254.1
    Conserved Domains (2) summary
    cd14690
    Location:180234
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  23. XM_038657746.1XP_038513674.1  cAMP-responsive element modulator isoform X18

    Related
    ENSCAFP00845002577.1, ENSCAFT00845003249.1
    Conserved Domains (2) summary
    cd14690
    Location:192246
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  24. XM_038657738.1XP_038513666.1  cAMP-responsive element modulator isoform X11

    Related
    ENSCAFP00845002572.1, ENSCAFT00845003243.1
    Conserved Domains (2) summary
    cd14690
    Location:243297
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  25. XM_038657730.1XP_038513658.1  cAMP-responsive element modulator isoform X4

    Conserved Domains (2) summary
    cd14690
    Location:292346
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:118154
    pKID; pKID domain
  26. XM_038657735.1XP_038513663.1  cAMP-responsive element modulator isoform X8

    Conserved Domains (2) summary
    cd14690
    Location:255309
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69105
    pKID; pKID domain
  27. XM_038657753.1XP_038513681.1  cAMP-responsive element modulator isoform X25

    Conserved Domains (1) summary
    cd14690
    Location:57111
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
  28. XM_038657751.1XP_038513679.1  cAMP-responsive element modulator isoform X23

    Related
    ENSCAFP00845002392.1, ENSCAFT00845003000.1
    Conserved Domains (1) summary
    cd14690
    Location:69123
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049262.1 Alternate UMICH_Zoey_3.1

    Range
    1809553..1859860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

    Range
    1853133..1903529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

    Range
    1973934..2024249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1843669..1893973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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