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COX8 Cytochrome c oxidase subunit 8 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40390, updated on 22-May-2022

Summary

Official Symbol
COX8provided by FlyBase
Official Full Name
Cytochrome c oxidase subunit 8provided by FlyBase
Primary source
FLYBASE:FBgn0263911
Locus tag
Dmel_CG7181
See related
AllianceGenome:FB:FBgn0263911
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
0554/18; anon-WO0118547.331; BcDNA:GH15688; CcO VIIc; CG7181; CoVIII; Dmel\CG7181; l(3)S055418; VIII
Summary
Predicted to enable cytochrome-c oxidase activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX8A (cytochrome c oxidase subunit 8A). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See COX8 in Genome Data Viewer
Location:
78D5-78D5; 3-47 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21538859..21539447, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21531959..21532547, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pickpocket 5 Neighboring gene Regulatory particle non-ATPase 10 Neighboring gene Vacuolar H[+] ATPase M9.7 subunit b Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cytochrome c oxidase subunit 8
Names
CG7181-PA
CG7181-PB
COX8-PA
COX8-PB
cytochrome c oxidase subunit VIII
lethal (3) S055418
subunit VIII
NP_001262169.1
NP_649328.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21538859..21539447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275240.1NP_001262169.1  cytochrome c oxidase subunit 8, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262169.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VP19
    Related
    FBpp0305654, FBtr0333464
    Conserved Domains (1) summary
    pfam02285
    Location:2665
    COX8; Cytochrome oxidase c subunit VIII
  2. NM_141071.2NP_649328.1  cytochrome c oxidase subunit 8, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649328.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VP19
    Related
    FBpp0078037, FBtr0078382
    Conserved Domains (1) summary
    pfam02285
    Location:2665
    COX8; Cytochrome oxidase c subunit VIII