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LGALS3 galectin 3 [ Canis lupus familiaris (dog) ]

Gene ID: 404021, updated on 28-Nov-2021

Summary

Official Symbol
LGALS3provided by VGNC
Official Full Name
galectin 3provided by VGNC
Primary source
VGNC:VGNC:42648
See related
EnsemblRapid:ENSCAFG00845015017
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
Gal-3; CBP 35; Galectin-3
Orthologs
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Genomic context

See LGALS3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (31236480..31254738)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (30752177..30763224)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (31288737..31299778)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (30846505..30857542)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (30923589..30934646)
105 previous assembly CanFam3.1 (GCF_000002285.3) 8 NC_006590.3 (30977438..30994711)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like Neighboring gene uncharacterized LOC100687432 Neighboring gene U6 spliceosomal RNA Neighboring gene DLG associated protein 5 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC111097041

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables chemoattractant activity IEA
Inferred from Electronic Annotation
more info
 
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
galectin-3
Names
35 kDa lectin
beta-galactosides-binding lectin
carbohydrate-binding protein 35
galactose-specific lectin 3
igE-binding protein
laminin-binding protein
lectin L-29
lectin, galactoside-binding, soluble, 3 (galectin 3)
mac-2 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197043.1NP_001183972.1  galectin-3

    See identical proteins and their annotated locations for NP_001183972.1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000053
    UniProtKB/TrEMBL
    E5Q8W5
    Related
    ENSCAFP00845021149.1, ENSCAFT00845026859.1
    Conserved Domains (2) summary
    PRK07764
    Location:13150
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00070
    Location:154281
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    31236480..31254738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038672858.1XP_038528786.1  galectin-3 isoform X1

    Conserved Domains (2) summary
    PRK07764
    Location:13150
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00070
    Location:154281
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    30846505..30857542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    30923589..30934646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    31288737..31299778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    30752177..30763224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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