U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Polr2H RNA polymerase II, I and III subunit H [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40415, updated on 4-Apr-2024

Summary

Official Symbol
Polr2Hprovided by FlyBase
Official Full Name
RNA polymerase II, I and III subunit Hprovided by FlyBase
Primary source
FLYBASE:FBgn0037121
Locus tag
Dmel_CG11246
See related
AllianceGenome:FB:FBgn0037121
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11246; Dmel\CG11246; Rpb8; RPB8
Summary
Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is expressed in anterior midgut primordium; embryonic/larval midgut; organism; and posterior midgut primordium. Orthologous to human POLR2H (RNA polymerase II, I and III subunit H). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
78E5-78E5; 3-47 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21728932..21729694)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21722032..21722794)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase I activity ISS
Inferred from Sequence or Structural Similarity
more info
 
contributes_to RNA polymerase II activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase II activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase III activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA transcription by RNA polymerase III ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transcription by RNA polymerase I ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase I complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase II, core complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of RNA polymerase III complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
RNA polymerase II, I and III subunit H
Names
CG11246-PA
Polr2H-PA
Rpb8
NP_649352.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21728932..21729694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141095.3NP_649352.1  RNA polymerase II, I and III subunit H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649352.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VNZ3
    Related
    FBpp0078086
    Conserved Domains (1) summary
    smart00658
    Location:2146
    RPOL8c; RNA polymerase subunit 8