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PTI pancreatic trypsin inhibitor [ Bos taurus (cattle) ]

Gene ID: 404172, updated on 14-Jan-2019

Summary

Gene symbol
PTI
Gene description
pancreatic trypsin inhibitor
See related
BGD:BT21240; Ensembl:ENSBTAG00000017328
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
BPI; BPTI

Genomic context

See PTI in Genome Data Viewer
Location:
chromosome: 13
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 13 NC_037340.1 (74296024..74300843)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104973892 Neighboring gene autophagy-related protein 13 pseudogene Neighboring gene serum basic protease inhibitor-like Neighboring gene WAP four-disulfide core domain 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD1.2 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Clone Names

  • MGC148815

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
potassium channel inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
protease binding IDA
Inferred from Direct Assay
more info
PubMed 
protease binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
serine-type endopeptidase inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
sulfate binding IDA
Inferred from Direct Assay
more info
PubMed 
zymogen binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
serine protease inhibitor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
pancreatic trypsin inhibitor
Names
aprotinin
basic protease inhibitor
trypsin ihibitor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001554.3NP_001001554.2  pancreatic trypsin inhibitor precursor

    See identical proteins and their annotated locations for NP_001001554.2

    Status: PROVISIONAL

    Source sequence(s)
    BC149368
    UniProtKB/TrEMBL
    A6QPK7
    Related
    ENSBTAP00000023042.5, ENSBTAT00000023042.5
    Conserved Domains (1) summary
    cd00109
    Location:3891
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    74296024..74300843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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