alphaTub85E alpha-Tubulin at 85E [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: alphaTub85Eprovided by FlyBase
Official Full Name: alpha-Tubulin at 85Eprovided by FlyBase
Primary source: FLYBASE:FBgn0003886
Locus tag: Dmel_CG9476
See related: AllianceGenome:FB:FBgn0003886
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 2t; 85E; a2t; ALPHA 85E; alpha-tub; alpha-Tub; alpha-Tub85E; alpha-tubulin; alpha2; alpha2t; alpha85E; alpha85E-tub; alphaTub; alphaTub2; alphaTub84E; alphatub85E; aTub85E; CG9476; Dmel\CG9476; DTA3; T; Tub; Tub1D; TUBA85E
Summary: A structural constituent of cytoskeleton. Involved in unidimensional cell growth. Located in cytoplasmic microtubule and spindle microtubule. Is expressed in several structures, including chordotonal organ; embryonic/larval muscle cell; embryonic/larval optic stalk; imaginal disc; and testis. Human ortholog(s) of this gene implicated in lissencephaly; lissencephaly 3; microcephaly; and visual epilepsy. Orthologous to human TUBA1A (tubulin alpha 1a). [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (9731221..9733250, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (5556943..5558972, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of cytoskeleton	IDA Inferred from Direct Assay more info	PubMed
enables structural constituent of cytoskeleton	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule-based process	IEA Inferred from Electronic Annotation more info
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in unidimensional cell growth	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic microtubule	IMP Inferred from Mutant Phenotype more info	PubMed
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in spindle microtubule	IMP Inferred from Mutant Phenotype more info	PubMed

Names: CG9476-PA; alpha tubulin; alpha-Tubulin; alpha-Tubulin 85E; alpha2-tubulin; alpha2tubulin; alpha85E-tubulin; alphaT; alphaTub85E-PA; alphatubulin; tubulin