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CG5276 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41373, updated on 4-Apr-2024

Summary

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Official Symbol
CG5276provided by FlyBase
Primary source
FLYBASE:FBgn0037900
Locus tag
Dmel_CG5276
See related
AllianceGenome:FB:FBgn0037900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5276
Summary
Enables adenosine-diphosphatase activity and dATP phosphohydrolase activity. Predicted to be involved in proteoglycan biosynthetic process. Is expressed in adult head. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Orthologous to human CANT1 (calcium activated nucleotidase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
86E5-86E5; 3-51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11431738..11433543)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7257460..7259265)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Spastizin Neighboring gene Ribosomal protein L24-like Neighboring gene D-aminoacyl-tRNA deacylase Neighboring gene Exonuclease 3'-5' domain-containing 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene sarcomere length short Neighboring gene mir-4945 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional characterization of ecto-5'-nucleotidases and apyrases in Drosophila melanogaster. Fenckova M, et al. Insect Biochem Mol Biol, 2011 Dec. PMID 21996016
  2. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
  3. A genome-wide CRISPR screen identifies DPM1 as a modifier of DPAGT1 deficiency and ER stress. Dalton HM, et al. PLoS Genet, 2022 Sep. PMID 36166480, Free PMC Article
  4. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ADP phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables GDP phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleoside diphosphate phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5276-PA
CG5276-PB
NP_001287287.1
NP_650074.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11431738..11433543
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141817.3 → NP_650074.1  uncharacterized protein Dmel_CG5276, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650074.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AN61, A0AN64, Q9VGN8
    Related
    FBpp0081866
    Conserved Domains (1) summary
    pfam06079
    Location:123 → 418
    Apyrase; Apyrase

  2. NM_001300358.1 → NP_001287287.1  uncharacterized protein Dmel_CG5276, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287287.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AN61, A0AN64, Q9VGN8
    Conserved Domains (1) summary
    pfam06079
    Location:123 → 418
    Apyrase; Apyrase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VGN8 Q9VGN8

Gene LinkOut

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