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dpr17 defective proboscis extension response 17 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41470, updated on 10-May-2024

Summary

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Official Symbol
dpr17provided by FlyBase
Official Full Name
defective proboscis extension response 17provided by FlyBase
Primary source
FLYBASE:FBgn0051361
Locus tag
Dmel_CG31361
See related
AllianceGenome:FB:FBgn0051361
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14737; CG14738; CG31361; CT34531; Dmel\CG31361; Dpr-17; Dpr17
Summary
Involved in synapse organization. Predicted to be integral component of plasma membrane. Predicted to be active in neuron projection membrane. Is expressed in several structures, including embryonic/larval circulatory system; embryonic/larval oenocyte; embryonic/larval salivary gland; extended germ band embryo; and yolk nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See dpr17 in Genome Data Viewer
Location:
87A8-87A9; 3-51 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12094876..12111420)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7920598..7937142)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ATPase 8B Neighboring gene transfer RNA:Lysine-TTT 2-5 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms. Peng J, et al. Elife, 2018 Mar 7. PMID 29513217, Free PMC Article
  2. Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons. Bornstein B, et al. EMBO J, 2021 Jun 15. PMID 33847376, Free PMC Article
  3. The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression. Panda D, et al. mBio, 2015 Apr 7. PMID 25852164, Free PMC Article
  4. Multiple Niche Compartments Orchestrate Stepwise Germline Stem Cell Progeny Differentiation. Tu R, et al. Curr Biol, 2021 Feb 22. PMID 33357404, Free PMC Article
  5. Genetic link between heme oxygenase and the signaling pathway of DNA damage in Drosophila melanogaster. Ida H, et al. Tohoku J Exp Med, 2013 Oct. PMID 24126234

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
defective proboscis extension response 17
Names
CG31361-PA
CG31361-PB
CG31361-PC
CG31361-PD
CG31361-PE
dpr17-PA
dpr17-PB
dpr17-PC
dpr17-PD
dpr17-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12094876..12111420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169451.2 → NP_731670.1  defective proboscis extension response 17, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731670.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SWT7, Q9VGD3
    Related
    FBpp0082016
    Conserved Domains (3) summary
    smart00408
    Location:524 → 605
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:521 → 612
    IG_like; Immunoglobulin like
    cl11960
    Location:415 → 507
    Ig; Immunoglobulin domain

  2. NM_001300368.1 → NP_001287297.1  defective proboscis extension response 17, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287297.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SWT7, Q9VGD3
    Conserved Domains (3) summary
    smart00408
    Location:524 → 605
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:521 → 612
    IG_like; Immunoglobulin like
    cl11960
    Location:415 → 507
    Ig; Immunoglobulin domain

  3. NM_001300369.1 → NP_001287298.1  defective proboscis extension response 17, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287298.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NNA1, Q9VGD2
    Conserved Domains (3) summary
    smart00408
    Location:368 → 449
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:365 → 456
    IG_like; Immunoglobulin like
    cl11960
    Location:259 → 351
    Ig; Immunoglobulin domain

  4. NM_001144567.2 → NP_001138039.1  defective proboscis extension response 17, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138039.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NNA1, Q9VGD2
    Conserved Domains (3) summary
    smart00408
    Location:368 → 449
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:365 → 456
    IG_like; Immunoglobulin like
    cl11960
    Location:259 → 351
    Ig; Immunoglobulin domain

  5. NM_169452.3 → NP_731671.1  defective proboscis extension response 17, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731671.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NNA1, Q9VGD2
    Related
    FBpp0082017
    Conserved Domains (3) summary
    smart00408
    Location:368 → 449
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:365 → 456
    IG_like; Immunoglobulin like
    cl11960
    Location:259 → 351
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SWT7 Q8SWT7
Q9VGD2 Q9VGD2
Q9VGD3 Q9VGD3

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