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Srlp Spliceosome-ribosome linker protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41533, updated on 10-May-2024

Summary

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Official Symbol
Srlpprovided by FlyBase
Official Full Name
Spliceosome-ribosome linker proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038049
Locus tag
Dmel_CG5844
See related
AllianceGenome:FB:FBgn0038049
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5844; Dmel\CG5844
Summary
Predicted to enable catalytic activity. Involved in cellular response to hypoxia. Is expressed in adult head; adult heart; and organism. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Srlp in Genome Data Viewer
Location:
87B10-87B10; 3-52 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12434098..12435643)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8259820..8261365)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Proteasome alpha2 subunit Neighboring gene Activator of SUMO 1 Neighboring gene Desaturase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Desaturase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The nucleotide changes governing cuticular hydrocarbon variation and their evolution in Drosophila melanogaster. Takahashi A, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11259658, Free PMC Article
  2. Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes. Yu J, et al. Cell Death Dis, 2019 Apr 1. PMID 30931935, Free PMC Article
  3. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Chen CL, et al. Proc Natl Acad Sci U S A, 2015 Sep 29. PMID 26362788, Free PMC Article
  4. An RNA interference screen identifies a novel regulator of target of rapamycin that mediates hypoxia suppression of translation in Drosophila S2 cells. Lee SJ, et al. Mol Biol Cell, 2008 Oct. PMID 18653470, Free PMC Article
  5. Drosophila histone locus bodies form by hierarchical recruitment of components. White AE, et al. J Cell Biol, 2011 May 16. PMID 21576393, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in cellular response to hypoxia IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
Spliceosome-ribosome linker protein
Names
CG5844-PA
Enoyl-CoA hydratase
Srlp-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12434098..12435643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141942.3 → NP_650199.1  Spliceosome-ribosome linker protein [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650199.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VG69
    Related
    FBpp0082063
    Conserved Domains (1) summary
    cl23717
    Location:49 → 259
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VG69 Q9VG69

Gene LinkOut

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