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ABCC4 ATP binding cassette subfamily C member 4 [ Gallus gallus (chicken) ]

Gene ID: 418791, updated on 3-Apr-2024

Summary

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Symbol
ABCC4provided by CGNC
Full Name
ATP binding cassette subfamily C member 4provided by CGNC
Primary source
CGNC:12680
See related
Ensembl:ENSGALG00010005402
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
37
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (146046970..146272143)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (146038600..146264446)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene UDP-glucose glycoprotein glucosyltransferase 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C3 Neighboring gene uncharacterized LOC121107106 Neighboring gene DAZ interacting zinc finger protein 1 Neighboring gene claudin 10 Neighboring gene uncharacterized LOC112531539 Neighboring gene uncharacterized LOC121108178

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Avian renal proximal tubule epithelium urate secretion is mediated by Mrp4. Bataille AM, et al. Am J Physiol Regul Integr Comp Physiol, 2008 Dec. PMID 18945957
  2. Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion. Ding X, et al. BMC Vet Res, 2019 May 30. PMID 31146764, Free PMC Article
  3. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results show that BCRP and MRP4 participate in renal and intestinal uric acid excretion in chickens and that BCRP is positively related to MRP4 mRNA expression
    Title: Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion.
  2. Avian renal proximal tubule epithelium urate secretion is mediated by Mrp4.
    Title: Avian renal proximal tubule epithelium urate secretion is mediated by Mrp4.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-binding cassette sub-family C member 4
Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
multidrug resistance protein 4
multidrug resistance-associated protein 4
NP_001025990.1
XP_040555535.1
XP_040555551.1
XP_046764110.1
XP_046764111.1
XP_046764112.1
XP_046764113.1
XP_046797289.1
XP_046797293.1
XP_046797294.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030819.2 → NP_001025990.1  ATP-binding cassette sub-family C member 4

    See identical proteins and their annotated locations for NP_001025990.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0XL38, F1P043, Q5ZMK2
    Related
    ENSGALP00010007420.1, ENSGALT00010012858.1
    Conserved Domains (5) summary
    cd03244
    Location:1044 → 1263
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:411 → 611
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    TIGR01271
    Location:11 → 1270
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    pfam00664
    Location:721 → 998
    ABC_membrane; ABC transporter transmembrane region
    cl00549
    Location:96 → 365
    ABC_membrane; ABC transporter transmembrane region

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    146046970..146272143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040699617.2 → XP_040555551.1  ATP-binding cassette sub-family C member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XL38
    Conserved Domains (1) summary
    PLN03130
    Location:8 → 1266
    PLN03130; ABC transporter C family member; Provisional

  2. XM_046941333.1 → XP_046797289.1  ATP-binding cassette sub-family C member 4 isoform X2

  3. XM_046941337.1 → XP_046797293.1  ATP-binding cassette sub-family C member 4 isoform X2

  4. XM_046941338.1 → XP_046797294.1  ATP-binding cassette sub-family C member 4 isoform X2

  5. XM_040699601.2 → XP_040555535.1  ATP-binding cassette sub-family C member 4 isoform X1

    UniProtKB/TrEMBL
    A0A165EAY6, A0A8V0XL38
    Related
    ENSGALP00010007419.1, ENSGALT00010012857.1
    Conserved Domains (1) summary
    PLN03130
    Location:2 → 1309
    PLN03130; ABC transporter C family member; Provisional

RNA

  1. XR_001462767.4 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    146038600..146264446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908155.1 → XP_046764111.1  ATP-binding cassette sub-family C member 4 isoform X2

  2. XM_046908156.1 → XP_046764112.1  ATP-binding cassette sub-family C member 4 isoform X2

  3. XM_046908157.1 → XP_046764113.1  ATP-binding cassette sub-family C member 4 isoform X2

  4. XM_046908154.1 → XP_046764110.1  ATP-binding cassette sub-family C member 4 isoform X1

    UniProtKB/TrEMBL
    A0A165EAY6

RNA

  1. XR_006932723.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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