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CG5404 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41901, updated on 10-May-2024

Summary

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Official Symbol
CG5404provided by FlyBase
Primary source
FLYBASE:FBgn0038354
Locus tag
Dmel_CG5404
See related
AllianceGenome:FB:FBgn0038354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5404
Summary
Predicted to enable anion:anion antiporter activity and sulfate transmembrane transporter activity. Predicted to be involved in sulfate transport and transmembrane transport. Predicted to be integral component of plasma membrane. Is expressed in adult head. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG5404 in Genome Data Viewer
Location:
89A2-89A2; 3-58 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15704676..15708434)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11530398..11534156)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45635 Neighboring gene long non-coding RNA:CR45636 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Drosophila genetic model of nephrolithiasis: transcriptional changes in response to diet induced stone formation. Chung VY, et al. BMC Urol, 2017 Nov 28. PMID 29183349, Free PMC Article
  2. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
  3. Copper homeostasis gene discovery in Drosophila melanogaster. Norgate M, et al. Biometals, 2007 Jun. PMID 17216353
  4. A gene-specific T2A-GAL4 library for Drosophila. Lee PT, et al. Elife, 2018 Mar 22. PMID 29565247, Free PMC Article
  5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5404-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    15704676..15708434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142225.3 → NP_650482.1  uncharacterized protein Dmel_CG5404 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650482.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95SI2, Q9VF45
    Related
    FBpp0082619
    Conserved Domains (2) summary
    cd07042
    Location:498 → 554
    STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
    TIGR00815
    Location:50 → 557
    sulP; high affinity sulphate transporter 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VF45 Q9VF45

Gene LinkOut

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