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FBXO32 F-box protein 32 [ Gallus gallus (chicken) ]

Gene ID: 420343, updated on 5-Mar-2024

Summary

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Symbol
FBXO32provided by CGNC
Full Name
F-box protein 32provided by CGNC
Primary source
CGNC:51229
See related
Ensembl:ENSGALG00010008245
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (137056903..137081428, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (137265710..137290196, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene ATPase family, AAA domain containing 2 Neighboring gene WDYHV motif containing 1 Neighboring gene uncharacterized LOC112531900 Neighboring gene kelch like family member 38 Neighboring gene uncharacterized LOC121109913 Neighboring gene annexin A13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. chicks having free access to feed for the first 24h increased their body weight and had decreased atrogin-1/MAFbx mRNA levels in their sartorius and pectoralis major muscles compared with the fasted chicks
    Title: Effects of first exogenous nutrients on the mRNA levels of atrogin-1/MAFbx and GLUT1 in the skeletal muscles of newly hatched chicks.
  2. Its enhanced expression causes muscle atrophy.
    Title: Effect of dexamethasone on the expression of atrogin-1/MAFbx in chick skeletal muscle.
  3. Atrogin-1/MAFbx mRNA expression in the smooth muscle of the gizzard was higher in meat-type chickens than in egg-type chickens.
    Title: Comparison of atrogin-1/MAFbx mRNA expression in the gizzards of egg- and meat-type chickens.
  4. atrogin-1/MAFbx mRNA is highly expressed in the smooth muscle of the chicken gizzard.
    Title: Atrogin-1/MAFbx, a muscle-specific ubiquitin ligase, is highly expressed in the smooth muscle of the chicken gizzard.
  5. The expression of atrogin-1 was regulated with diets varying in protein and energy content.
    Title: Regulators of protein metabolism are affected by cyclical nutritional treatments with diets varying in protein and energy content.
  6. refeeding stimulates phosphorylation of Akt/FOXO, resulting in a decrease in atrogin-1 expression in skeletal muscle of chicks
    Title: Effects of fasting and refeeding on expression of atrogin-1 and Akt/FOXO signaling pathway in skeletal muscle of chicks.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-box only protein 32
Names
atrogin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389309.2 → NP_001376238.1  F-box only protein 32

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000044
    UniProtKB/TrEMBL
    Q5ZHM6
    Related
    ENSGALP00010011272.1, ENSGALT00010019724.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    137056903..137081428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005852621.2 RNA Sequence

  2. XR_006935157.1 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    137265710..137290196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_006933395.1 RNA Sequence

  2. XR_006933394.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001030956.1: Suppressed sequence

    Description
    NM_001030956.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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