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ABCB1LA ATP-binding cassette, sub-family B (MDR/TAP), member 1-like A [ Gallus gallus (chicken) ]

Gene ID: 420534, updated on 3-Apr-2024

Summary

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Official Symbol
ABCB1LAprovided by CGNC
Official Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 1-like Aprovided by CGNC
Primary source
CGNC:51277
See related
Ensembl:ENSGALG00010005222
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ABCB4
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Genomic context

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Location:
chromosome: 2
Exon count:
30
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (20571871..20613752, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (20600867..20642748, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA binding domain containing 7 Neighboring gene oleoyl-ACP hydrolase Neighboring gene carnitine O-octanoyltransferase Neighboring gene ATP binding cassette subfamily B member 1 Neighboring gene RUN domain containing 3B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent translocase ABCB1; phosphatidylcholine translocator ABCB4
Names
ATP-binding cassette, sub-family B (MDR/TAP), member 1
ATP-binding cassette, sub-family B (MDR/TAP), member 4
member 4
sub-family B (MDR/TAP)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    20571871..20613752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938334.1 → XP_046794290.1  ATP-dependent translocase ABCB1 isoform X2

    Related
    ENSGALP00010006924.1, ENSGALT00010012360.1

  2. XM_040695688.2 → XP_040551622.1  ATP-dependent translocase ABCB1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XJP5, A0A8V0XS81
    Related
    ENSGALP00010006920.1, ENSGALT00010012356.1
    Conserved Domains (1) summary
    PTZ00265
    Location:8 → 1238
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  3. XM_040695687.2 → XP_040551621.1  phosphatidylcholine translocator ABCB4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJP5
    Conserved Domains (1) summary
    PTZ00265
    Location:39 → 1253
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  4. XM_025148400.3 → XP_025004168.2  ATP-dependent translocase ABCB1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XJP5
    Conserved Domains (1) summary
    PTZ00265
    Location:39 → 1290
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  5. XM_025148401.3 → XP_025004169.2  phosphatidylcholine translocator ABCB4 isoform X5

    Conserved Domains (1) summary
    PTZ00265
    Location:19 → 983
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  6. XM_040695689.2 → XP_040551623.1  phosphatidylcholine translocator ABCB4 isoform X6

    Conserved Domains (2) summary
    cd03249
    Location:250 → 489
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    COG1132
    Location:1 → 491
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]

  7. XM_040695690.2 → XP_040551624.1  phosphatidylcholine translocator ABCB4 isoform X7

    Conserved Domains (2) summary
    cd03249
    Location:163 → 402
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    cd18578
    Location:1 → 146
    ABC_6TM_Pgp_ABCB1_D2_like; Six-transmembrane helical domain 2 (TMD2) of P-glycoprotein 1 (Pgp) and related proteins

RNA

  1. XR_005857439.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    20600867..20642748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046912801.1 → XP_046768757.1  ATP-dependent translocase ABCB1 isoform X2

  2. XM_040665649.2 → XP_040521583.1  ATP-dependent translocase ABCB1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XJP5
    Conserved Domains (1) summary
    PTZ00265
    Location:8 → 1238
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  3. XM_040665648.2 → XP_040521582.1  phosphatidylcholine translocator ABCB4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJP5
    Conserved Domains (1) summary
    PTZ00265
    Location:39 → 1253
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  4. XM_040665647.2 → XP_040521581.1  ATP-dependent translocase ABCB1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XJP5
    Conserved Domains (1) summary
    PTZ00265
    Location:39 → 1290
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  5. XM_040665650.2 → XP_040521584.1  phosphatidylcholine translocator ABCB4 isoform X5

    Conserved Domains (1) summary
    PTZ00265
    Location:19 → 983
    PTZ00265; multidrug resistance protein (mdr1); Provisional

  6. XM_040665651.2 → XP_040521585.1  phosphatidylcholine translocator ABCB4 isoform X6

    Conserved Domains (2) summary
    cd03249
    Location:250 → 489
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    COG1132
    Location:1 → 491
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]

  7. XM_040665652.2 → XP_040521586.1  phosphatidylcholine translocator ABCB4 isoform X7

    Conserved Domains (2) summary
    cd03249
    Location:163 → 402
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    cd18578
    Location:1 → 146
    ABC_6TM_Pgp_ABCB1_D2_like; Six-transmembrane helical domain 2 (TMD2) of P-glycoprotein 1 (Pgp) and related proteins

RNA

  1. XR_005847405.2 RNA Sequence

Nucleotide Protein
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