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DAAM2 dishevelled associated activator of morphogenesis 2 [ Gallus gallus (chicken) ]

Gene ID: 421422, updated on 3-Apr-2024

Summary

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Symbol
DAAM2provided by CGNC
Full Name
dishevelled associated activator of morphogenesis 2provided by CGNC
Primary source
CGNC:7646
See related
Ensembl:ENSGALG00010020120
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See DAAM2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
32
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (28421135..28628458, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (28345618..28552959, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110312 Neighboring gene uncharacterized LOC107052916 Neighboring gene molybdenum cofactor synthesis 1 Neighboring gene kinesin family member 6 Neighboring gene potassium two pore domain channel subfamily K member 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord. Lee HK, et al. Dev Cell, 2012 Jan 17. PMID 22227309, Free PMC Article
  2. Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system. Kida Y, et al. Brain Res Dev Brain Res, 2004 Oct 15. PMID 15464228
  3. A set of testis-specific novel genes collected from a collection of Korean Native Chicken ESTs. Shin JH, et al. Anim Genet, 2005 Aug. PMID 16026346
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.
    Title: Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.
  2. involved in pivotal steps in neuronal cell differentiation and movement
    Title: Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of oligodendrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disheveled-associated activator of morphogenesis 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396527.1 → NP_001383456.1  disheveled-associated activator of morphogenesis 2

    Status: VALIDATED

    Source sequence(s)
    BX933940, CO770487, CV036952, JAENSK010000063
    UniProtKB/TrEMBL
    A0A8V0ZDB0, A0A8V0ZJC0
    Related
    ENSGALP00010028698.1, ENSGALT00010048607.1
    Conserved Domains (4) summary
    pfam06367
    Location:312 → 516
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:686 → 1070
    FH2; Formin Homology 2 Domain
    pfam06133
    Location:510 → 594
    Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
    pfam06371
    Location:124 → 309
    Drf_GBD; Diaphanous GTPase-binding Domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28421135..28628458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040697627.2 → XP_040553561.1  disheveled-associated activator of morphogenesis 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZBV3
    Related
    ENSGALP00010028694.1, ENSGALT00010048603.1
    Conserved Domains (2) summary
    smart00498
    Location:639 → 1082
    FH2; Formin Homology 2 Domain
    pfam06367
    Location:264 → 468
    Drf_FH3; Diaphanous FH3 Domain

  2. XM_040697625.2 → XP_040553559.1  disheveled-associated activator of morphogenesis 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZDB0, A0A8V0ZJC0
    Conserved Domains (4) summary
    pfam06367
    Location:312 → 516
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:686 → 1070
    FH2; Formin Homology 2 Domain
    pfam06133
    Location:510 → 594
    Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
    pfam06371
    Location:124 → 309
    Drf_GBD; Diaphanous GTPase-binding Domain

  3. XM_046938818.1 → XP_046794774.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  4. XM_046938816.1 → XP_046794772.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  5. XM_046938814.1 → XP_046794770.1  disheveled-associated activator of morphogenesis 2 isoform X4

  6. XM_040697626.2 → XP_040553560.1  disheveled-associated activator of morphogenesis 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZDB0, A0A8V0ZJC0
    Related
    ENSGALP00010028700.1, ENSGALT00010048609.1
    Conserved Domains (4) summary
    pfam06367
    Location:312 → 516
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:686 → 1070
    FH2; Formin Homology 2 Domain
    pfam06133
    Location:510 → 594
    Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
    pfam06371
    Location:124 → 309
    Drf_GBD; Diaphanous GTPase-binding Domain

  7. XM_046938817.1 → XP_046794773.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  8. XM_004935382.5 → XP_004935439.2  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  9. XM_025148875.3 → XP_025004643.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Related
    ENSGALP00010028691.1, ENSGALT00010048600.1
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  10. XM_004935381.5 → XP_004935438.2  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  11. XM_025148874.3 → XP_025004642.2  disheveled-associated activator of morphogenesis 2 isoform X2

  12. XM_046938813.1 → XP_046794769.1  disheveled-associated activator of morphogenesis 2 isoform X1

  13. XM_046938815.1 → XP_046794771.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  14. XM_015283804.4 → XP_015139290.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28345618..28552959 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040667571.2 → XP_040523505.1  disheveled-associated activator of morphogenesis 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZBV3
    Conserved Domains (2) summary
    smart00498
    Location:639 → 1082
    FH2; Formin Homology 2 Domain
    pfam06367
    Location:264 → 468
    Drf_FH3; Diaphanous FH3 Domain

  2. XM_040667569.2 → XP_040523503.1  disheveled-associated activator of morphogenesis 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZDB0, A0A8V0ZJC0
    Conserved Domains (4) summary
    pfam06367
    Location:312 → 516
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:686 → 1070
    FH2; Formin Homology 2 Domain
    pfam06133
    Location:510 → 594
    Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
    pfam06371
    Location:124 → 309
    Drf_GBD; Diaphanous GTPase-binding Domain

  3. XM_046913819.1 → XP_046769775.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  4. XM_046913817.1 → XP_046769773.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  5. XM_046913815.1 → XP_046769771.1  disheveled-associated activator of morphogenesis 2 isoform X4

  6. XM_040667570.2 → XP_040523504.1  disheveled-associated activator of morphogenesis 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZDB0, A0A8V0ZJC0
    Conserved Domains (4) summary
    pfam06367
    Location:312 → 516
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:686 → 1070
    FH2; Formin Homology 2 Domain
    pfam06133
    Location:510 → 594
    Com_YlbF; Control of competence regulator ComK, YlbF/YmcA
    pfam06371
    Location:124 → 309
    Drf_GBD; Diaphanous GTPase-binding Domain

  7. XM_046913818.1 → XP_046769774.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  8. XM_040667574.2 → XP_040523508.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  9. XM_040667578.2 → XP_040523512.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  10. XM_040667573.2 → XP_040523507.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain

  11. XM_040667567.2 → XP_040523501.2  disheveled-associated activator of morphogenesis 2 isoform X2

  12. XM_046913814.1 → XP_046769770.1  disheveled-associated activator of morphogenesis 2 isoform X1

  13. XM_046913816.1 → XP_046769772.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/TrEMBL
    A0A5H1ZRJ8

  14. XM_040667579.2 → XP_040523513.1  disheveled-associated activator of morphogenesis 2 isoform X5

    UniProtKB/Swiss-Prot
    A0A1D5P1Y2, A0A1D5P556, A0A1D5PPK5, E1BS28
    UniProtKB/TrEMBL
    A0A5H1ZRJ8
    Conserved Domains (3) summary
    pfam06367
    Location:234 → 438
    Drf_FH3; Diaphanous FH3 Domain
    pfam02181
    Location:608 → 992
    FH2; Formin Homology 2 Domain
    pfam06371
    Location:46 → 231
    Drf_GBD; Diaphanous GTPase-binding Domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1D5P556.2 GenPept UniProtKB/Swiss-Prot:A0A1D5P556

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