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CPE carboxypeptidase E [ Gallus gallus (chicken) ]

Gene ID: 422424, updated on 5-Mar-2024

Summary

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Symbol
CPEprovided by CGNC
Full Name
carboxypeptidase Eprovided by CGNC
Primary source
CGNC:66432
See related
Ensembl:ENSGALG00010007882
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (23337542..23384245)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (23403746..23450530)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 2 Neighboring gene uncharacterized LOC121110790 Neighboring gene methylsterol monooxygenase 1 Neighboring gene uncharacterized LOC107052719 Neighboring gene serine/arginine repetitive matrix protein 3-like Neighboring gene tolloid like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus. Zhang X, et al. Cell Tissue Res, 2009 Sep. PMID 19603184, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. co-existence of CgA and CpE in identical neuroendocrine cells in the transition zone between the cortex and medulla of the thymus
    Title: Carboxypeptidase E, an essential element of the regulated secretory pathway, is expressed and partially co-localized with chromogranin A in chicken thymus.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metallocarboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
carboxypeptidase E
XP_040527749.1
XP_046772890.1
XP_046796521.1
XP_420392.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    23337542..23384245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_420392.8 → XP_420392.3  carboxypeptidase E isoform X1

    UniProtKB/TrEMBL
    R4GFJ0
    Related
    ENSGALP00010010303.1, ENSGALT00010018753.1
    Conserved Domains (2) summary
    cd11308
    Location:368 → 442
    Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
    cd03865
    Location:46 → 364
    M14_CPE; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase E subgroup

  2. XM_046940565.1 → XP_046796521.1  carboxypeptidase E isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    23403746..23450530
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040671815.2 → XP_040527749.1  carboxypeptidase E isoform X1

    UniProtKB/TrEMBL
    R4GFJ0
    Conserved Domains (2) summary
    cd11308
    Location:368 → 442
    Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain
    cd03865
    Location:46 → 364
    M14_CPE; Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase E subgroup

  2. XM_046916934.1 → XP_046772890.1  carboxypeptidase E isoform X2

Nucleotide Protein
Heading Accession and Version

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