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SAV1 salvador family WW domain containing protein 1 [ Gallus gallus (chicken) ]

Gene ID: 423578, updated on 5-Mar-2024

Summary

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Symbol
SAV1provided by CGNC
Full Name
salvador family WW domain containing protein 1provided by CGNC
Primary source
CGNC:9373
See related
Ensembl:ENSGALG00010019350
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See SAV1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (57655415..57666791, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (57530332..57541646, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 5 Neighboring gene atlastin GTPase 1 Neighboring gene ninein Neighboring gene abhydrolase domain containing 12B Neighboring gene phosphorylase, glycogen, liver

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary. Lyu Z, et al. PLoS One, 2016. PMID 27505353, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SAV1 can inhibit proliferation of the granulosa cells
    Title: The Hippo/MST Pathway Member SAV1 Plays a Suppressive Role in Development of the Prehierarchical Follicles in Hen Ovary.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hippo signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein salvador homolog 1
Names
salvador homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    57655415..57666791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015276749.4 → XP_015132235.1  protein salvador homolog 1 isoform X1

    UniProtKB/TrEMBL
    E1C3T7
    Related
    ENSGALP00010027863.1, ENSGALT00010046802.1
    Conserved Domains (1) summary
    cd00201
    Location:204 → 234
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

  2. XM_040701820.2 → XP_040557754.1  protein salvador homolog 1 isoform X2

    Conserved Domains (1) summary
    cd00201
    Location:204 → 234
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    57530332..57541646 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040672873.2 → XP_040528807.1  protein salvador homolog 1 isoform X1

    UniProtKB/TrEMBL
    E1C3T7

  2. XM_040672874.2 → XP_040528808.1  protein salvador homolog 1 isoform X2

    Conserved Domains (1) summary
    cd00201
    Location:204 → 234
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
Nucleotide Protein Strain
Heading Accession and Version

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