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CG10887 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42399, updated on 10-May-2024

Summary

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Official Symbol
CG10887provided by FlyBase
Primary source
FLYBASE:FBgn0038773
Locus tag
Dmel_CG10887
See related
AllianceGenome:FB:FBgn0038773
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10887
Summary
Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Predicted to be involved in positive regulation of transcription elongation from RNA polymerase II promoter. Predicted to be part of Cdc73/Paf1 complex. Predicted to be active in nucleus. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG10887 in Genome Data Viewer
Location:
92D1-92D1; 3-68 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20114838..20117139)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15940560..15942861)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Rhodopsin 3 Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 92a Neighboring gene long non-coding RNA:CR42836

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. Bergman CM, et al. Genome Biol, 2002. PMID 12537575, Free PMC Article
  2. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article
  3. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
  4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  5. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA polymerase II C-terminal domain phosphoserine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Cdc73/Paf1 complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10887-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20114838..20117139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142609.2 → NP_650866.1  uncharacterized protein Dmel_CG10887 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650866.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDP7
    Related
    FBpp0083273
    Conserved Domains (1) summary
    pfam04004
    Location:396 → 548
    Leo1; Leo1-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDP7 Q9VDP7

Gene LinkOut

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