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GLP1R glucagon like peptide 1 receptor [ Gallus gallus (chicken) ]

Gene ID: 428573, updated on 5-Mar-2024

Summary

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Symbol
GLP1Rprovided by CGNC
Full Name
glucagon like peptide 1 receptorprovided by CGNC
Primary source
CGNC:7660
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GLP-1R
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (28981897..29061242, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (28909400..28988745, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101748090 Neighboring gene potassium two pore domain channel subfamily K member 5 Neighboring gene SAYSVFN motif domain containing 1 Neighboring gene uncharacterized LOC107052913 Neighboring gene dynein axonemal heavy chain 8 Neighboring gene glyoxalase I Neighboring gene BTB domain containing 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Huang G, et al. Domest Anim Endocrinol, 2012 Jul. PMID 22417644
  2. Expression of proglucagon and proglucagon-derived peptide hormone receptor genes in the chicken. Richards MP, et al. Gen Comp Endocrinol, 2008 Apr 1. PMID 18299131

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The 5'-flanking region of cGLP1R gene displays promoter activities in cultured HepG2 and HEK293 cells, suggesting that it may control cGLP1R gene transcription in chicken tissues, including nonpancreatic tissues.
    Title: Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants.
  2. GLP-1 receptor genes were highly expressed in the gastrointestinal tract, brain, pancreas and abdominal fat
    Title: Expression of proglucagon and proglucagon-derived peptide hormone receptor genes in the chicken.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucagon receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glucagon-like peptide 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135551.1 → NP_001129023.1  glucagon-like peptide 1 receptor precursor

    See identical proteins and their annotated locations for NP_001129023.1

    Status: PROVISIONAL

    Source sequence(s)
    EU770586
    UniProtKB/TrEMBL
    B4ZY91, F1N8H7
    Conserved Domains (2) summary
    pfam00002
    Location:137 → 394
    7tm_2; 7 transmembrane receptor (Secretin family)
    pfam02793
    Location:60 → 127
    HRM; Hormone receptor domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28981897..29061242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28909400..28988745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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