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Esp Epidermal stripes and patches [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42962, updated on 10-May-2024

Summary

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Official Symbol
Espprovided by FlyBase
Official Full Name
Epidermal stripes and patchesprovided by FlyBase
Primary source
FLYBASE:FBgn0013953
Locus tag
Dmel_CG7005
See related
AllianceGenome:FB:FBgn0013953
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7005; Dmel\CG7005
Summary
Predicted to enable anion:anion antiporter activity and sulfate transmembrane transporter activity. Involved in negative regulation of female receptivity, post-mating. Predicted to be integral component of plasma membrane. Is expressed in several structures, including apoptotic amnioserosa; ectoderm; ectoderm anlage; extended germ band embryo; and presumptive embryonic/larval system. Orthologous to human SLC26A11 (solute carrier family 26 member 11). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Esp in Genome Data Viewer
Location:
96B1-96B1; 3-86 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24841935..24850412)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20667657..20676134)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45216 Neighboring gene sosie Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Nicastrin Neighboring gene Histone deacetylase 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ion and solute transport by Prestin in Drosophila and Anopheles. Hirata T, et al. J Insect Physiol, 2012 Apr. PMID 22321763, Free PMC Article
  2. Molecular evolution of the sex peptide network in Drosophila. McGeary MK, et al. J Evol Biol, 2020 May. PMID 31991034
  3. FOXO-regulated transcription restricts overgrowth of Tsc mutant organs. Harvey KF, et al. J Cell Biol, 2008 Feb 25. PMID 18299344, Free PMC Article
  4. A double-negative gene regulatory circuit underlies the virgin behavioral state. Garaulet DL, et al. Cell Rep, 2021 Jul 6. PMID 34233178, Free PMC Article
  5. Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye. Zhang T, et al. Dev Dyn, 2005 Nov. PMID 16145661

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of female receptivity, post-mating IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epidermal stripes and patches
Names
CG7005-PA
CG7005-PB
Esp-PA
Esp-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24841935..24850412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202353.2 → NP_001189282.1  epidermal stripes and patches, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189282.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U6Q2, Q9VC29
    Conserved Domains (3) summary
    cd07042
    Location:545 → 623
    STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
    TIGR00815
    Location:86 → 615
    sulP; high affinity sulphate transporter 1
    cl23746
    Location:103 → 520
    HCO3_cotransp; HCO3- transporter family

  2. NM_079766.4 → NP_524490.2  epidermal stripes and patches, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524490.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U6Q2, Q9VC29
    Related
    FBpp0084081
    Conserved Domains (3) summary
    cd07042
    Location:545 → 623
    STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
    TIGR00815
    Location:86 → 615
    sulP; high affinity sulphate transporter 1
    cl23746
    Location:103 → 520
    HCO3_cotransp; HCO3- transporter family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9U6Q2 Q9U6Q2
Q9VC29 Q9VC29

Gene LinkOut

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