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PRPF19 pre-mRNA processing factor 19 [ Gallus gallus (chicken) ]

Gene ID: 430767, updated on 5-Mar-2024

Summary

Symbol
PRPF19provided by CGNC
Full Name
pre-mRNA processing factor 19provided by CGNC
Primary source
CGNC:10410
See related
Ensembl:ENSGALG00010020449
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (228680..232794, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (222449..226565, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene bile acid-CoA:amino acid N-acyltransferase Neighboring gene zona pellucida glycoprotein 1 Neighboring gene transmembrane protein 109 Neighboring gene transmembrane protein 132A Neighboring gene CD6 molecule

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of Prp19 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of U2-type catalytic step 1 spliceosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
pre-mRNA-processing factor 19
Names
PRP19/PSO4 homolog
PRP19/PSO4 pre-mRNA processing factor 19 homolog
RING-type E3 ubiquitin transferase PRP19
NP_001034420.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039331.3NP_001034420.3  pre-mRNA-processing factor 19

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000212
    UniProtKB/Swiss-Prot
    P84167, Q5ZMA2
    UniProtKB/TrEMBL
    A0A1D5PZS0
    Related
    ENSGALP00010029236.1, ENSGALT00010049470.1
    Conserved Domains (4) summary
    cd00200
    Location:223503
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:224262
    7WD40; WD40 repeat [structural motif]
    cd16656
    Location:456
    RING-Ubox_PRP19; U-box domain, a modified RING finger, found in pre-mRNA-processing factor 19 (Prp19) and similar proteins
    pfam08606
    Location:69133
    Prp19; Prp19/Pso4-like

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    228680..232794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    222449..226565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)