U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MME membrane metalloendopeptidase [ Homo sapiens (human) ]

Gene ID: 4311, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
MMEprovided by HGNC
Official Full Name
membrane metalloendopeptidaseprovided by HGNC
Primary source
HGNC:HGNC:7154
See related
Ensembl:ENSG00000196549 MIM:120520; AllianceGenome:HGNC:7154
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NEP; SFE; CD10; CALLA; CMT2T; SCA43
Summary
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]
Expression
Biased expression in duodenum (RPKM 88.5), kidney (RPKM 83.7) and 8 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MME in Genome Data Viewer
Location:
3q25.2
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (155024202..155183729)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (157798155..157957709)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (154741991..154901518)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374170 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:154605732-154606931 Neighboring gene uncharacterized LOC105374171 Neighboring gene NANOG hESC enhancer GRCh37_chr3:154639118-154639653 Neighboring gene Sharpr-MPRA regulatory region 12262 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:154842003-154842759 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:154842760-154843515 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:154896874-154897105 Neighboring gene Sharpr-MPRA regulatory region 4432 Neighboring gene MPRA-validated peak4871 silencer Neighboring gene long intergenic non-protein coding RNA 1487 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:154999620-155000162 Neighboring gene small transmembrane regulator of ion transport 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure. Luo HY, et al. Eur J Clin Pharmacol, 2023 May. PMID 36976322
  2. Predictive role of neostromal CD10 expression in breast cancer patients treated with neoadjuvant chemotherapy. Olah O, et al. Pathol Oncol Res, 2022. PMID 36685105, Free PMC Article
  3. Stromal CD10 expression in gastric adenocarcinoma. Aziz SJ, et al. J Med Life, 2022 May. PMID 35815076, Free PMC Article
  4. A nonsense mutation in MME gene associates with autosomal recessive late-onset Charcot-Marie-Tooth disease. Jamiri Z, et al. Mol Genet Genomic Med, 2022 May. PMID 35212467, Free PMC Article
  5. Stromal expression of CD10 in invasive breast carcinoma and its association with tumour stage, grade, ER, PR and HER2 status. Kamarudin NA, et al. Malays J Pathol, 2021 Dec. PMID 34958060

See all (360) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. "Evaluation of neprilysin activity in Adipose-Derived stem cells from Alzheimer's disease patients".
    Title: "Evaluation of neprilysin activity in Adipose-Derived stem cells from Alzheimer's disease patients".
  2. miRNA-211-5p inhibition enhances the protective effect of hucMSC-derived exosome in Abeta1-40 -induced SH-SY5Y cells by increasing NEP expression.
    Title: miRNA-211-5p inhibition enhances the protective effect of hucMSC-derived exosome in Aβ(1-40) -induced SH-SY5Y cells by increasing NEP expression.
  3. Induction of ICAM1 in Brain Vessels is Implicated in an Early AD Pathogenesis by Modulating Neprilysin.
    Title: Induction of ICAM1 in Brain Vessels is Implicated in an Early AD Pathogenesis by Modulating Neprilysin.
  4. Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer.
    Title: Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer.
  5. Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure.
    Title: Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure.
  6. Dengue Virus Increases the Expression of TREM-1 and CD10 on Human Neutrophils.
    Title: Dengue Virus Increases the Expression of TREM-1 and CD10 on Human Neutrophils.
  7. Predictive role of neostromal CD10 expression in breast cancer patients treated with neoadjuvant chemotherapy.
    Title: Predictive role of neostromal CD10 expression in breast cancer patients treated with neoadjuvant chemotherapy.
  8. Expression Profile of CD10, BCL-2, p63, and EMA in the Normal Skin and Basal Cell Carcinomas: An Immunohistochemical Reappraisal.
    Title: Expression Profile of CD10, BCL-2, p63, and EMA in the Normal Skin and Basal Cell Carcinomas: An Immunohistochemical Reappraisal.
  9. Stromal CD10 expression in gastric adenocarcinoma.
    Title: Stromal CD10 expression in gastric adenocarcinoma.
  10. A nonsense mutation in MME gene associates with autosomal recessive late-onset Charcot-Marie-Tooth disease.
    Title: A nonsense mutation in MME gene associates with autosomal recessive late-onset Charcot-Marie-Tooth disease.
Submit: New GeneRIF Correction See all GeneRIFs (291)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Charcot-Marie-Tooth disease axonal type 2T
MedGen: C4015635 OMIM: 617017 GeneReviews: Not available
Compare labs
Charcot-Marie-Tooth disease type 2
MedGen: C0270914 GeneReviews: Charcot-Marie-Tooth Hereditary Neuropathy Overview
Compare labs
Spinocerebellar ataxia 43
MedGen: C4310763 OMIM: 617018 GeneReviews: Not available
Compare labs

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

Go to the top of the page Help

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp120-treated vaginal epithelial cells show upregulation of membrane metallo-endopeptidase (MME, CD10) expression as compared to untreated control PubMed
Tat tat HIV-1 Tat, which is found in the brains of patients with HIV-1 infection, inhibits the amyloid beta (Abeta)-degrading enzyme, neprilysin (NEP) PubMed
tat CD10/Nep inhibits HIV-1 Tat dimerization in Jurkat T-cells PubMed
Vif vif HIV-1 Vif upregulates the expression of membrane metallo-endopeptidase (MME) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC126681, MGC126707, DKFZp686O16152

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cardiolipin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables endopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables endopeptidase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables endopeptidase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables exopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables metalloendopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metalloendopeptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables metalloendopeptidase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables oligopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatidylserine binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta clearance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amyloid-beta clearance IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amyloid-beta clearance IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in amyloid-beta clearance ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in amyloid-beta clearance by cellular catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amyloid-beta clearance by cellular catabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in amyloid-beta clearance by cellular catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in amyloid-beta metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in bradykinin catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to UV-A IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to UV-B IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to cytokine stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in creatinine metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in hormone catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in kidney development IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in learning or memory IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in lung development IEA
Inferred from Electronic Annotation
more info
  
involved_in neuropeptide processing IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in peptide metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in placenta development IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of neurogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proteolysis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in proteolysis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in replicative senescence IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to estrogen IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of pain ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in substance P catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IGI
Inferred from Genetic Interaction
more info
 PubMed 
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in brush border IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell surface NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in dendrite ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in early endosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular exosome HDA PubMed 
located_in focal adhesion HDA PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuron projection terminus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in neuronal cell body IGI
Inferred from Genetic Interaction
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in presynapse IGI
Inferred from Genetic Interaction
more info
 PubMed 
located_in secretory granule membrane TAS
Traceable Author Statement
more info
  
located_in synapse ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in synaptic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neprilysin
Names
atriopeptidase
common acute lymphocytic leukemia antigen
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
neprilysin-390
neprilysin-411
neutral endopeptidase 24.11
skin fibroblast elastase
NP_000893.2
NP_001341571.1
NP_001341572.1
NP_001341573.1
NP_009218.2
NP_009219.2
NP_009220.2
XP_006713710.1
XP_011511158.1
XP_011511159.1
XP_047304113.1
XP_054202544.1
XP_054202545.1
XP_054202546.1
XP_054202547.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051105.1 RefSeqGene

    Range
    61196..164581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000902.5 → NP_000893.2  neprilysin isoform a

    See identical proteins and their annotated locations for NP_000893.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, BM151602, X07166
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000418525.1, ENST00000460393.6
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  2. NM_001354642.2 → NP_001341571.1  neprilysin isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, AK291761
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000420389.1, ENST00000492661.5
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  3. NM_001354643.1 → NP_001341572.1  neprilysin isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, AC117384, Y00811
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000417079.1, ENST00000493237.5
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  4. NM_001354644.1 → NP_001341573.1  neprilysin isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 3' UTR and coding sequence compared to variant 2b. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC117384, BC106070
    Consensus CDS
    CCDS87157.1
    UniProtKB/TrEMBL
    Q3KQS6
    Related
    ENSP00000372450.3, ENST00000382989.7

  5. NM_007287.4 → NP_009218.2  neprilysin isoform a

    See identical proteins and their annotated locations for NP_009218.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1bis) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, AC117384, DB142029, X07166
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000502021.2, ENST00000675418.2
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  6. NM_007288.3 → NP_009219.2  neprilysin isoform a

    See identical proteins and their annotated locations for NP_009219.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2a) contains an alternate 5' UTR exon, compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, AC117384
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000419653.1, ENST00000462745.5
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  7. NM_007289.4 → NP_009220.2  neprilysin isoform a

    See identical proteins and their annotated locations for NP_009220.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2b) is the longest transcript and includes alternate exon 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a).
    Source sequence(s)
    AC106724, AC117384
    Consensus CDS
    CCDS3172.1
    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000353679.2, ENST00000360490.7
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    155024202..155183729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047448157.1 → XP_047304113.1  neprilysin isoform X1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4

  2. XM_006713647.5 → XP_006713710.1  neprilysin isoform X1

    See identical proteins and their annotated locations for XP_006713710.1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000505211.1, ENST00000680057.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  3. XM_011512857.3 → XP_011511159.1  neprilysin isoform X1

    See identical proteins and their annotated locations for XP_011511159.1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Related
    ENSP00000505690.1, ENST00000680282.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  4. XM_011512856.3 → XP_011511158.1  neprilysin isoform X1

    See identical proteins and their annotated locations for XP_011511158.1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
    UniProtKB/TrEMBL
    B7ZKY6
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    157798155..157957709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054346570.1 → XP_054202545.1  neprilysin isoform X1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4

  2. XM_054346571.1 → XP_054202546.1  neprilysin isoform X1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4

  3. XM_054346569.1 → XP_054202544.1  neprilysin isoform X1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4

  4. XM_054346572.1 → XP_054202547.1  neprilysin isoform X1

    UniProtKB/Swiss-Prot
    A8K6U6, D3DNJ9, P08473, Q3MIX4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P08473.2 GenPept UniProtKB/Swiss-Prot:P08473

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous