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CAH9 Carbonic anhydrase 9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43264, updated on 10-May-2024

Summary

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Official Symbol
CAH9provided by FlyBase
Official Full Name
Carbonic anhydrase 9provided by FlyBase
Primary source
FLYBASE:FBgn0039486
Locus tag
Dmel_CG6074
See related
AllianceGenome:FB:FBgn0039486
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
caix; CAIX; CG6074; CT19053; Dmel\CG6074
Summary
Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be active in plasma membrane. Is expressed in adult head and embryonic/larval midgut. Orthologous to human CA6 (carbonic anhydrase 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CAH9 in Genome Data Viewer
Location:
97E2-97E2; 3-92 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27102988..27106184, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22928710..22931906, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene eater Neighboring gene Juvenile hormone binding protein 11 Neighboring gene antisense RNA:CR45209 Neighboring gene genderblind Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A glial amino-acid transporter controls synapse strength and courtship in Drosophila. Grosjean Y, et al. Nat Neurosci, 2008 Jan. PMID 18066061, Free PMC Article
  2. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
  3. HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals. Bandarra D, et al. Dis Model Mech, 2015 Feb. PMID 25510503, Free PMC Article
  4. Molecular mechanism and functional significance of acid generation in the Drosophila midgut. Overend G, et al. Sci Rep, 2016 Jun 2. PMID 27250760, Free PMC Article
  5. The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis. Zhou F, et al. Metabolites, 2021 May 6. PMID 34066348, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carbonic anhydrase 9
Names
CAH9-PA
CG6074-PA
caix
carbonic anhydrase IX
NP_651535.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    27102988..27106184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143278.2 → NP_651535.1  carbonic anhydrase 9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651535.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NLI8, Q9VB76
    Related
    FBpp0084503
    Conserved Domains (1) summary
    smart01057
    Location:25 → 282
    Carb_anhydrase; Eukaryotic-type carbonic anhydrase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VB76 Q9VB76

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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