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Zfp975 zinc finger protein 975 [ Mus musculus (house mouse) ]

Gene ID: 434179, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp975provided by MGI
Official Full Name
zinc finger protein 975provided by MGI
Primary source
MGI:MGI:3648690
See related
Ensembl:ENSMUSG00000069727 AllianceGenome:MGI:3648690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5595; mszf88; EG434179
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryo. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 2.0), placenta adult (RPKM 1.7) and 22 other tissues See more
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Genomic context

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See Zfp975 in Genome Data Viewer
Location:
7 B3; 7 28.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (42309529..42342191, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (42660105..42692810, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18744 Neighboring gene predicted gene, 21028 Neighboring gene zinc finger protein 977 Neighboring gene zinc finger protein 976 Neighboring gene STARR-seq mESC enhancer starr_18745 Neighboring gene STARR-seq mESC enhancer starr_18747 Neighboring gene predicted gene, 38998 Neighboring gene zinc finger protein 120-like Neighboring gene ribosomal protein L18A pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC434179

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008427.2 → NP_001008427.1  uncharacterized protein LOC434179 isoform 1

    See identical proteins and their annotated locations for NP_001008427.1

    Status: VALIDATED

    Source sequence(s)
    AC102628
    Consensus CDS
    CCDS39926.1
    UniProtKB/TrEMBL
    Q6NVD6
    Related
    ENSMUSP00000103626.2, ENSMUST00000107992.2
    Conserved Domains (5) summary
    smart00349
    Location:4 → 46
    KRAB; krueppel associated box
    COG5048
    Location:98 → 514
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:441 → 461
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 43
    KRAB; KRAB box
    pfam13465
    Location:173 → 197
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001419398.1 → NP_001406327.1  uncharacterized protein LOC434179 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102628

RNA

  1. NR_185070.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC102628

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    42309529..42342191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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