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CG11837 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43429, updated on 19-Jun-2024

Summary

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Official Symbol
CG11837provided by FlyBase
Primary source
FLYBASE:FBgn0039627
Locus tag
Dmel_CG11837
See related
AllianceGenome:FB:FBgn0039627
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dim1; Dmel\CG11837
Summary
Predicted to enable rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation. Predicted to be active in mitochondrial matrix. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval muscle system; and extended germ band embryo. Orthologous to human DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG11837 in Genome Data Viewer
Location:
98F6-98F6; 3-97 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29049493..29050721)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24875215..24876443)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cleavage and polyadenylation specificity factor 100 Neighboring gene Slu7 Neighboring gene Protein C kinase 98E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear ribosome biogenesis mediated by the DIM1A rRNA dimethylase is required for organized root growth and epidermal patterning in Arabidopsis. Wieckowski Y, et al. Plant Cell, 2012 Jul. PMID 22829145, Free PMC Article
  2. Drosophila growth and development in the absence of dMyc and dMnt. Pierce SB, et al. Dev Biol, 2008 Mar 15. PMID 18241851, Free PMC Article
  3. Transcriptome analysis of a long-lived natural Drosophila variant: a prominent role of stress- and reproduction-genes in lifespan extension. Doroszuk A, et al. BMC Genomics, 2012 May 4. PMID 22559237, Free PMC Article
  4. The computational analysis of scientific literature to define and recognize gene expression clusters. Raychaudhuri S, et al. Nucleic Acids Res, 2003 Aug 1. PMID 12888516, Free PMC Article
  5. Mating-responsive genes in reproductive tissues of female Drosophila melanogaster. Mack PD, et al. Proc Natl Acad Sci U S A, 2006 Jul 5. PMID 16798875, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables rRNA (adenine-N6,N6-)-dimethyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (adenine-N6,N6-)-dimethyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in rRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA modification IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11837-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29049493..29050721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143403.4 → NP_651660.1  uncharacterized protein Dmel_CG11837 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651660.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VAQ5
    Related
    FBpp0084729
    Conserved Domains (1) summary
    PTZ00338
    Location:16 → 305
    PTZ00338; dimethyladenosine transferase-like protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VAQ5.1 Q9VAQ5

Gene LinkOut

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