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Clec2f C-type lectin domain family 2, member f [ Mus musculus (house mouse) ]

Gene ID: 435921, updated on 8-Feb-2024

Summary

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Official Symbol
Clec2fprovided by MGI
Official Full Name
C-type lectin domain family 2, member fprovided by MGI
Primary source
MGI:MGI:3522133
See related
Ensembl:ENSMUSG00000089728 AllianceGenome:MGI:3522133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clrc; Clrz; Clr-c; Clec2f-ps
Summary
Predicted to enable natural killer cell lectin-like receptor binding activity. Predicted to be located in cell surface and endoplasmic reticulum. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC2D (C-type lectin domain family 2 member D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
6 F3; 6 63.12 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (128985766..128998305)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (129008803..129021342)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 2, member g Neighboring gene STARR-seq mESC enhancer starr_17470 Neighboring gene interferon stimulated exonuclease gene 20-like 2 pseudogene Neighboring gene cDNA sequence BC064078 Neighboring gene STARR-seq mESC enhancer starr_17472 Neighboring gene killer cell lectin-like receptor subfamily B member 1F Neighboring gene STARR-seq mESC enhancer starr_17473 Neighboring gene STARR-seq mESC enhancer starr_17475 Neighboring gene C-type lectin domain family 2, member e

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse. Kveberg L, et al. Immunogenetics, 2011 Jul. PMID 21409442, Free PMC Article
  2. The expression and function of the NKRP1 receptor family in C57BL/6 mice. Aust JG, et al. J Immunol, 2009 Jul 1. PMID 19535641
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables natural killer cell lectin-like receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
C-type lectin domain family 2 member F
Names
C lectin-related protein c
C-type lectin domain family 2, member f, pseudogene
C-type lectin-related protein C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277202.1 → NP_001264131.1  C-type lectin domain family 2 member F

    See identical proteins and their annotated locations for NP_001264131.1

    Status: VALIDATED

    Source sequence(s)
    JF792240
    Consensus CDS
    CCDS90127.1
    UniProtKB/TrEMBL
    F5CSM8
    Related
    ENSMUSP00000158978.2, ENSMUST00000204981.2
    Conserved Domains (1) summary
    PHA02642
    Location:86 → 201
    PHA02642; C-type lectin-like protein; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    128985766..128998305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506362.2 → XP_006506425.1  C-type lectin domain family 2 member F isoform X1

    See identical proteins and their annotated locations for XP_006506425.1

    UniProtKB/TrEMBL
    F5CSM8
    Conserved Domains (1) summary
    PHA02642
    Location:86 → 201
    PHA02642; C-type lectin-like protein; Provisional

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_015898.1: Suppressed sequence

    Description
    NG_015898.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VI21.1 GenPept UniProtKB/Swiss-Prot:Q8VI21

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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