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CG15553 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43677, updated on 10-May-2024

Summary

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Official Symbol
CG15553provided by FlyBase
Primary source
FLYBASE:FBgn0039817
Locus tag
Dmel_CG15553
See related
AllianceGenome:FB:FBgn0039817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15553
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to human SLC46A1 (solute carrier family 46 member 1) and SLC46A3 (solute carrier family 46 member 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG15553 in Genome Data Viewer
Location:
100B2-100B2; 3-102 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31098868..31101169, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26924590..26926891, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sox100B Neighboring gene uncharacterized protein Neighboring gene mayo Neighboring gene Proteasome alpha3 subunit, Testis-specific

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Validation of Candidate Genes Detected by Genomic Feature Models. Rohde PD, et al. G3 (Bethesda), 2018 May 4. PMID 29519937, Free PMC Article
  2. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
  3. The Drosophila Tis11 protein and its effects on mRNA expression in flies. Choi YJ, et al. J Biol Chem, 2014 Dec 19. PMID 25342740, Free PMC Article
  4. Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila. Lamiable O, et al. Proc Natl Acad Sci U S A, 2016 Jan 19. PMID 26739560, Free PMC Article
  5. A Glio-Protective Role of mir-263a by Tuning Sensitivity to Glutamate. Aw SS, et al. Cell Rep, 2017 May 30. PMID 28564598

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15553-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    31098868..31101169 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143584.4 → NP_651841.3  uncharacterized protein Dmel_CG15553 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651841.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VA14
    Conserved Domains (2) summary
    pfam07690
    Location:96 → 469
    MFS_1; Major Facilitator Superfamily
    cl21472
    Location:97 → 239
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VA14 Q9VA14

Gene LinkOut

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