Gycbeta100B Guanylyl cyclase beta-subunit at 100B [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gycbeta100Bprovided by FlyBase
Official Full Name: Guanylyl cyclase beta-subunit at 100Bprovided by FlyBase
Primary source: FLYBASE:FBgn0013973
Locus tag: Dmel_CG1470
See related: AllianceGenome:FB:FBgn0013973
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG1470; Dgc beta 1; dgcb1; dgcbeta1; Dgcbeta1; Dmel\CG1470; Gbeta100B; gyc beta; Gycbeta-100B; gycbeta100B; sGC-beta; sGCbeta1; sGCbeta100B
Summary: Enables guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and trans-synaptic signaling by nitric oxide, modulating synaptic transmission. Part of guanylate cyclase complex, soluble. Is expressed in adult head and adult optic lobe. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (31134392..31178278)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (26960114..27004000)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables guanylate cyclase activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanylate cyclase activity	IDA Inferred from Direct Assay more info	PubMed
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables phosphorus-oxygen lyase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cGMP-mediated signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cyclic nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in response to oxygen levels	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of guanylate cyclase complex, soluble	IBA Inferred from Biological aspect of Ancestor more info
part_of guanylate cyclase complex, soluble	IDA Inferred from Direct Assay more info	PubMed

NP_524603.2

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The following sections contain reference sequences that belong to a specific genome build. Explain