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CG17698 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 4379919, updated on 10-May-2024

Summary

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Official Symbol
CG17698provided by FlyBase
Primary source
FLYBASE:FBgn0040056
Locus tag
Dmel_CG17698
See related
AllianceGenome:FB:FBgn0040056
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CAMKIIb; CAMKIIB; CG40297; Dmel\CG17698
Summary
Predicted to enable calcium ion binding activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to be located in cytoplasm. Orthologous to several human genes including CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG17698 in Genome Data Viewer
Location:
80F9-80F9; 3-47 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (23737960..23749058)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (23731060..23742158)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45736 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43941

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Li C, et al. Cell, 2009 May 1. PMID 19395009, Free PMC Article
  2. A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues. Parsons LM, et al. G3 (Bethesda), 2017 Aug 7. PMID 28611255, Free PMC Article
  3. Genetic and Molecular Analysis of Essential Genes in Centromeric Heterochromatin of the Left Arm of Chromosome 3 in Drosophila melanogaster. Syrzycka M, et al. G3 (Bethesda), 2019 May 7. PMID 30948422, Free PMC Article
  4. Compartmentalized calcium transients trigger dendrite pruning in Drosophila sensory neurons. Kanamori T, et al. Science, 2013 Jun 21. PMID 23722427
  5. The mRNA transportome of the BicD/Egl transport machinery. Vazquez-Pianzola P, et al. RNA Biol, 2017 Jan 2. PMID 27801632, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: 23739755-23739845 mobile_element_type = transposon:INE-1{}2324
  • Loc: 23741578-23742357 mobile_element_type = transposon:3S18{}2989
  • Loc: 23742418-23742556 mobile_element_type = transposon:INE-1{}2325
  • Loc: 23743186-23743363 mobile_element_type = transposon:INE-1{}2332
  • Loc: 23745072-23745302 mobile_element_type = transposon:Idefix{}2919

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17698-PA
CG17698-PD
CG17698-PE
CG17698-PF
NP_001036632.1
NP_001036633.2
NP_001036634.1
NP_001262237.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    23737960..23749058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001043168.2 → NP_001036633.2  uncharacterized protein Dmel_CG17698, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036633.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A4V2C3
    Conserved Domains (2) summary
    smart00220
    Location:283 → 573
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14118
    Location:288 → 574
    STKc_CAMKK; Catalytic domain of the Serine/Threonine kinase, Calmodulin Dependent Protein Kinase Kinase

  2. NM_001275308.1 → NP_001262237.1  uncharacterized protein Dmel_CG17698, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262237.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PGA6
    Conserved Domains (2) summary
    smart00220
    Location:283 → 486
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:288 → 492
    PKc_like; Protein Kinases, catalytic domain

  3. NM_001043169.2 → NP_001036634.1  uncharacterized protein Dmel_CG17698, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036634.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5LJP6
    Conserved Domains (2) summary
    smart00220
    Location:283 → 555
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14118
    Location:288 → 556
    STKc_CAMKK; Catalytic domain of the Serine/Threonine kinase, Calmodulin Dependent Protein Kinase Kinase

  4. NM_001043167.2 → NP_001036632.1  uncharacterized protein Dmel_CG17698, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036632.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5LJP5
    Conserved Domains (2) summary
    smart00220
    Location:1 → 245
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:1 → 246
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4V2C3 A4V2C3
M9PGA6 M9PGA6
Q5LJP5 Q5LJP5
Q5LJP6 Q5LJP6

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