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mAcon1 Mitochondrial aconitase 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44149, updated on 6-Jul-2021

Summary

Official Symbol
mAcon1provided by FlyBase
Official Full Name
Mitochondrial aconitase 1provided by FlyBase
Primary source
FLYBASE:FBgn0010100
Locus tag
Dmel_CG9244
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
acon; Acon; ACON-1; aconitase; AconM; BEST:GH10550; CG9244; Dmel\CG9244; hsp60; i204; i59; l(2)07054; m-acon; m-Acon; M-Acon; mAc; mAcon; mACON
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Genomic context

See mAcon1 in Genome Data Viewer
Location:
39A7-39A7; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21168570..21173185)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21168570..21173185)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phospholipase D family member 3 Neighboring gene Nibbler Neighboring gene antisense RNA:CR44910 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small Cajal body-specific RNA : PsiU2-38.40.42 Neighboring gene uncharacterized protein Neighboring gene burgundy

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the mAcon1 gene: The mAcon1 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables aconitate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables aconitate hydratase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables aconitate hydratase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tricarboxylic acid cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
mitochondrial aconitase 1
Names
ACONITASE
CG9244-PB
CG9244-PD
CG9244-PE
CG9244-PF
m-aconitase
mAcon1-PB
mAcon1-PD
mAcon1-PE
mAcon1-PF
mitochondrial aconitase
NP_001097186.2
NP_001163030.1
NP_001286119.1
NP_524708.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21168570..21173185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299190.1NP_001286119.1  mitochondrial aconitase 1, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286119.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIE8
    Related
    FBpp0312178, FBtr0346587
    Conserved Domains (3) summary
    cd01584
    Location:102513
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:595743
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:52782
    aconitase_mito; aconitate hydratase, mitochondrial
  2. NM_001103716.2NP_001097186.2  mitochondrial aconitase 1, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097186.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIE8
    Related
    FBpp0310408, FBtr0343871
    Conserved Domains (3) summary
    cd01584
    Location:102513
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:595743
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:52782
    aconitase_mito; aconitate hydratase, mitochondrial
  3. NM_001169559.2NP_001163030.1  mitochondrial aconitase 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163030.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIE8
    Related
    FBpp0289654, FBtr0300425
    Conserved Domains (3) summary
    cd01584
    Location:102513
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:595743
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:52782
    aconitase_mito; aconitate hydratase, mitochondrial
  4. NM_079969.5NP_524708.1  mitochondrial aconitase 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524708.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIE8
    Related
    FBpp0081002, FBtr0081473
    Conserved Domains (3) summary
    cd01584
    Location:102513
    AcnA_Mitochondrial; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle
    cd01578
    Location:595743
    AcnA_Mitochon_Swivel; Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes ...
    TIGR01340
    Location:52782
    aconitase_mito; aconitate hydratase, mitochondrial
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