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COX5A cytochrome c oxidase subunit 5A [ Bos taurus (cattle) ]

Gene ID: 444878, updated on 5-Mar-2024

Summary

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Official Symbol
COX5Aprovided by VGNC
Official Full Name
cytochrome c oxidase subunit 5Aprovided by VGNC
Primary source
VGNC:VGNC:27636
See related
BGD:BT26852; Ensembl:ENSBTAG00000017267
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (33765160..33776139)

Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 5 Neighboring gene ribonuclease P and MRP subunit p25 Neighboring gene family with sequence similarity 219 member B Neighboring gene mannose phosphate isomerase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amino acid sequence of subunit V of bovine heart cytochrome oxidase, the heme alpha-containing subunit. Tanaka M, et al. J Biol Chem, 1979 May 25. PMID 220224
  2. Tissue-specific differences between heart and liver cytochrome c oxidase. Yanamura W, et al. Biochemistry, 1988 Jun 28. PMID 2844245
  3. X-ray structure of azide-bound fully oxidized cytochrome c oxidase from bovine heart at 2.9 A resolution. Fei MJ, et al. Acta Crystallogr D Biol Crystallogr, 2000 May. PMID 10771420
  4. Structure analysis of bovine heart cytochrome c oxidase at 2.8 A resolution. Tomizaki T, et al. Acta Crystallogr D Biol Crystallogr, 1999 Jan. PMID 10089392
  5. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Tsukihara T, et al. Science, 1996 May 24. PMID 8638158

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC133649

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of mitochondrial respiratory chain complex IV IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytochrome c oxidase subunit 5A, mitochondrial
Names
cytochrome c oxidase polypeptide Va
cytochrome c oxidase subunit Va
mitochondrial cytochrome c oxidase subunit 5a
NP_001002891.1
XP_005221971.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002891.1 → NP_001002891.1  cytochrome c oxidase subunit 5A, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001002891.1

    Status: PROVISIONAL

    Source sequence(s)
    AY528254
    UniProtKB/Swiss-Prot
    P00426, Q32LF6, Q6QRN2
    Related
    ENSBTAP00000022949.3, ENSBTAT00000022949.5
    Conserved Domains (1) summary
    cd00923
    Location:47 → 148
    Cyt_c_Oxidase_Va; Cytochrome c oxidase subunit Va. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    33765160..33776139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005221914.3 → XP_005221971.1  cytochrome c oxidase subunit 5A, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_005221971.1

    UniProtKB/Swiss-Prot
    P00426, Q32LF6, Q6QRN2
    Conserved Domains (1) summary
    cd00923
    Location:47 → 148
    Cyt_c_Oxidase_Va; Cytochrome c oxidase subunit Va. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00426.2 GenPept UniProtKB/Swiss-Prot:P00426

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