sfxn1 sideroflexin 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sfxn1provided by ZNC
Official Full Name: sideroflexin 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-45
See related: Ensembl:ENSDARG00000019963 AllianceGenome:ZFIN:ZDB-GENE-040801-45
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:100851
Summary: Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to act upstream of or within amino acid transport; ion transport; and transmembrane transport. Predicted to be located in membrane and mitochondrion. Predicted to be integral component of membrane. Predicted to be integral component of mitochondrial inner membrane. Is expressed in nervous system; pronephric duct; and yolk syncytial layer. Orthologous to human SFXN1 (sideroflexin 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (49078447..49110308, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (50090839..50122543, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables monoatomic ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amino acid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within hemoglobin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleate erythrocyte maturation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in serine import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sideroflexin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003537.2 → NP_001003537.1 sideroflexin-1

See identical proteins and their annotated locations for NP_001003537.1

Status: PROVISIONAL

Source sequence(s)

BC078297

UniProtKB/TrEMBL

Q6DC00

Related

ENSDARP00000003500.4, ENSDART00000023654.6

Conserved Domains (1) summary

pfam03820
Location:16 → 322

Mtc; Tricarboxylate carrier

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

49078447..49110308 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005169627.4 → XP_005169684.1 sideroflexin-1 isoform X1

UniProtKB/TrEMBL

A0A8M2BGW1, F1QA91, F1R5W5

Conserved Domains (1) summary

pfam03820
Location:16 → 322

Mtc; Tricarboxylate carrier