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fgf8/17/18 fibroblast growth factor 8/17/18 [ Ciona intestinalis (vase tunicate) ]

Gene ID: 445650, updated on 21-Dec-2023

Summary

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Gene symbol
fgf8/17/18
Gene description
fibroblast growth factor 8/17/18
See related
Ensembl:ENSCING00000009302
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ciona intestinalis
Lineage
Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
Also known as
Fgf18
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Genomic context

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See fgf8/17/18 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Annotation release Status Assembly Chr Location
104 current KH (GCF_000224145.3) 5 NC_020170.2 (2812422..2824624, complement)

Chromosome 5 - NC_020170.2Genomic Context describing neighboring genes Neighboring gene protein PLANT CADMIUM RESISTANCE 2-like Neighboring gene F-box/WD repeat-containing protein 4-like Neighboring gene nucleoplasmin-like protein ANO39 Neighboring gene uncharacterized LOC100185169

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_020170.2 Chromosome 5 Reference KH Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis. Racioppi C, et al. Nat Commun, 2014 Sep 5. PMID 25189217, Free PMC Article
  2. FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos. Yasuo H, et al. Dev Biol, 2007 Feb 1. PMID 17022960
  3. Neural tube patterning by Ephrin, FGF and Notch signaling relays. Stolfi A, et al. Development, 2011 Dec. PMID 22110057
  4. Region specific gene expressions in the central nervous system of the ascidian embryo. Imai KS, et al. Mech Dev, 2002 Dec. PMID 14516697
  5. Fgf genes in the basal chordate Ciona intestinalis. Satou Y, et al. Dev Genes Evol, 2002 Oct. PMID 12373588

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.
    Title: Fibroblast growth factor signalling controls nervous system patterning and pigment cell formation in Ciona intestinalis.
  2. It was shown that the developing motor ganglion is patterned by sequential Ephrin/FGF8/MAPK and Delta/Notch signaling events. FGF8/MAPK attenuation by a localized Ephrin Ab signal specified posterior neuronal subtypes.
    Title: Neural tube patterning by Ephrin, FGF and Notch signaling relays.
  3. Study demonstrates that FGF9/16/20 acts solely during the initial induction step of notochord formation and that, subsequently, FGF8/17/18 together with FGF9/16/20 is involved in the following maintenance step.
    Title: FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type 1 fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type 2 fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor 8/17/18
Names
Ci-Fgf8/17/18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032476.1 → NP_001027648.1  fibroblast growth factor 8/17/18

    See identical proteins and their annotated locations for NP_001027648.1

    Status: PROVISIONAL

    Source sequence(s)
    AB086096
    UniProtKB/TrEMBL
    A0A1W2VN86, F7A6I3, Q8I6J5
    Related
    ENSCINP00000018902, ENSCINT00000018902
    Conserved Domains (1) summary
    pfam00167
    Location:56 → 181
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KH Primary Assembly

Genomic

  1. NC_020170.2 Reference KH Primary Assembly

    Range
    2812422..2824624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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