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msxb msxb homeoprotein [ Ciona intestinalis (vase tunicate) ]

Gene ID: 445677, updated on 21-Dec-2023

Summary

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Gene symbol
msxb
Gene description
msxb homeoprotein
See related
Ensembl:ENSCING00000009129
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ciona intestinalis
Lineage
Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
Also known as
Ci-msxb
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Genomic context

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See msxb in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
104 current KH (GCF_000224145.3) 2 NC_020167.2 (5773526..5775829)

Chromosome 2 - NC_020167.2Genomic Context describing neighboring genes Neighboring gene PRELI domain-containing protein 1, mitochondrial-like Neighboring gene glutamine--tRNA ligase-like Neighboring gene uncharacterized LOC108950884 Neighboring gene uncharacterized LOC100182818

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_020167.2 Chromosome 2 Reference KH Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Msxb is a core component of the genetic circuitry specifying the dorsal and ventral neurogenic midlines in the ascidian embryo. Roure A, et al. Dev Biol, 2016 Jan 1. PMID 26592100
  2. Regulatory elements controlling Ci-msxb tissue-specific expression during Ciona intestinalis embryonic development. Russo MT, et al. Dev Biol, 2004 Mar 15. PMID 15013810
  3. Identification and developmental expression of Ci-msxb: a novel homologue of Drosophila msh gene in Ciona intestinalis. Aniello F, et al. Mech Dev, 1999 Oct. PMID 10525197
  4. Transcriptional regulation of the retinoic acid receptor in the dorsal midline epidermis in the Ciona intestinalis embryo. Koyano R, et al. Dev Growth Differ, 2009 Dec. PMID 19824898
  5. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Imai KS, et al. Development, 2004 Aug. PMID 15269171

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Msxb would be the primary midline gene integrating inputs from the ventral and dorsal inducers and launching a pan-midline transcriptional program.
    Title: Msxb is a core component of the genetic circuitry specifying the dorsal and ventral neurogenic midlines in the ascidian embryo.
  2. Msxb and SoxB1 synergistically activate the RAR enhancer in the dorsal midline epidermis.
    Title: Transcriptional regulation of the retinoic acid receptor in the dorsal midline epidermis in the Ciona intestinalis embryo.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in embryonic morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
msxb homeoprotein
Names
transcription factor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032496.1 → NP_001027668.1  msxb homeoprotein

    See identical proteins and their annotated locations for NP_001027668.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ132758
    UniProtKB/TrEMBL
    A0A1W2VNB1, F6S3B3, Q9XZR1
    Related
    ENSCINP00000018527, ENSCINT00000018527
    Conserved Domains (1) summary
    pfam00046
    Location:184 → 237
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KH Primary Assembly

Genomic

  1. NC_020167.2 Reference KH Primary Assembly

    Range
    5773526..5775829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases