U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nectin2.L nectin cell adhesion molecule 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 447468, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
nectin2.L
Official Full Name
nectin cell adhesion molecule 2 L homeolog
Primary source
Xenbase:XB-GENE-947435
Locus tag
XELAEV_18036021mg
See related
EnsemblRapid:ENSXLAG00005021769
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ed4; prr; higr; hveb; hvec; ofc7; prr1; prr2; pvrr; cd111; cd112; pvrl1; pvrl2; pvrr1; pvrr2; sk-12; clped1; pvrl2.L; nectin-1; nectin-2
Annotation information
Annotation category: partial on reference assembly
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 7L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (114826968..114858438)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (104296840..104328403)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase CBL-like Neighboring gene basal cell adhesion molecule (Lutheran blood group) L homeolog Neighboring gene translocase of outer mitochondrial membrane 40 homolog L homeolog Neighboring gene apolipoprotein E L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Morita H, et al. Development, 2010 Apr. PMID 20332149, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC81721

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within acrosome assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within coreceptor-mediated virion attachment to host cell IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within establishment of mitochondrion localization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fusion of virus membrane with host plasma membrane IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of immunoglobulin mediated immune response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of mast cell activation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of viral entry into host cell IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within susceptibility to T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within susceptibility to natural killer cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical junction complex IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular exosome IEA
Inferred from Electronic Annotation
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
nectin cell adhesion molecule 2 L homeolog
Names
nectin 2
nectin-2alpha
poliovirus receptor-related 1 (herpesvirus entry mediator C)
poliovirus receptor-related 2 (herpesvirus entry mediator B) L homeolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094175.1 → NP_001087644.1  nectin cell adhesion molecule 2 L homeolog precursor

    See identical proteins and their annotated locations for NP_001087644.1

    Status: PROVISIONAL

    Source sequence(s)
    BC081035
    UniProtKB/TrEMBL
    A0A974CGT6, Q66J72
    Related
    ENSXLAP00005063944.1, ENSXLAT00005065458.1
    Conserved Domains (4) summary
    cd05718
    Location:32 → 122
    Ig1_PVR_like; First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins
    cd07703
    Location:125 → 217
    Ig2_Nectin-2_like; Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins
    smart00410
    Location:24 → 121
    IG_like; Immunoglobulin like
    pfam13927
    Location:240 → 294
    Ig_3; Immunoglobulin domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    114826968..114858438
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.