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PL-D placental lactogen PL-D [ Pan troglodytes (chimpanzee) ]

Gene ID: 449574, updated on 29-Mar-2024

Summary

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Gene symbol
PL-D
Gene description
placental lactogen PL-D
Locus tag
CK820_G0011608
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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Genomic context

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See PL-D in Genome Data Viewer
Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (77003913..77005560, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (75188363..75191184, complement)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 Neighboring gene intercellular adhesion molecule 1 Neighboring gene growth hormone 2 Neighboring gene chorionic somatomammotropin hormone 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expansion and divergence of the GH locus between spider monkey and chimpanzee. Revol De Mendoza A, et al. Gene, 2004 Jul 21. PMID 15246530
  2. The chimpanzee GH locus: composition, organization, and evolution. Pérez-Maya AA, et al. Mamm Genome, 2012 Jun. PMID 22290452
  3. Molecular evolution of growth hormone gene family in old world monkeys and hominoids. Ye C, et al. Gene, 2005 May 9. PMID 15848116

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth hormone receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to nutrient levels IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: placental lactogen PL-D; placental lactogen PL-D
Names
CSH2
placental lactogen PL-C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008998.1 → NP_001008998.1  placental lactogen PL-D precursor

    See identical proteins and their annotated locations for NP_001008998.1

    Status: PROVISIONAL

    Source sequence(s)
    AY146628
    UniProtKB/TrEMBL
    A0A2J8QYF6, H6U7G6, Q866T8
    Conserved Domains (1) summary
    cd10285
    Location:35 → 215
    somatotropin_like; Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    77003913..77005560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063799171.1 → XP_063655241.1  LOW QUALITY PROTEIN: placental lactogen PL-D

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases