eipr1 EARP complex and GARP complex interacting protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eipr1provided by ZNC
Official Full Name: EARP complex and GARP complex interacting protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-167
See related: Ensembl:ENSDARG00000043417 AllianceGenome:ZFIN:ZDB-GENE-041010-167
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tssc1; zgc:101720
Summary: Predicted to be involved in endocytic recycling and protein ubiquitination. Predicted to be located in Golgi apparatus. Orthologous to human EIPR1 (EARP complex and GARP complex interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (51262556..51345046)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (51173510..51225032)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in endocytic recycling	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: EARP-interacting protein homolog; protein TSSC1

Names: tumor suppressing subtransferable candidate 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006065.1 → NP_001006065.1 EARP-interacting protein homolog

See identical proteins and their annotated locations for NP_001006065.1

Status: PROVISIONAL

Source sequence(s)

BC083257

UniProtKB/Swiss-Prot

Q5XJP1

UniProtKB/TrEMBL

A7YYD3

Related

ENSDARP00000150706.1, ENSDART00000186748.1

Conserved Domains (3) summary

COG2319
Location:104 → 374

WD40; WD40 repeat [General function prediction only]

sd00039
Location:68 → 125

7WD40; WD40 repeat [structural motif]

cl02567
Location:139 → 299

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007128.7 Reference GRCz11 Primary Assembly

Range

51262556..51345046

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021467152.1 → XP_021322827.1 protein TSSC1 isoform X1

UniProtKB/TrEMBL

A0A8M6Z264, F1R8B7

Conserved Domains (2) summary

sd00039
Location:72 → 129

7WD40; WD40 repeat [structural motif]

cl25539
Location:143 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017351629.2 → XP_017207118.1 protein TSSC1 isoform X1

UniProtKB/TrEMBL

A0A8M6Z264, F1R8B7

Related

ENSDARP00000154183.1, ENSDART00000189066.1

Conserved Domains (2) summary

sd00039
Location:72 → 129

7WD40; WD40 repeat [structural motif]

cl25539
Location:143 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_017351628.2 → XP_017207117.1 protein TSSC1 isoform X1

UniProtKB/TrEMBL

A0A8M6Z264, F1R8B7

Related

ENSDARP00000154537.1, ENSDART00000181606.1

Conserved Domains (2) summary

sd00039
Location:72 → 129

7WD40; WD40 repeat [structural motif]

cl25539
Location:143 → 303

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...