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ITGA8 integrin subunit alpha 8 [ Pan troglodytes (chimpanzee) ]

Gene ID: 450323, updated on 3-Apr-2024

Summary

Official Symbol
ITGA8provided by VGNC
Official Full Name
integrin subunit alpha 8provided by VGNC
Primary source
VGNC:VGNC:12349
Locus tag
CK820_G0041179
See related
Ensembl:ENSPTRG00000002321
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See ITGA8 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (28676130..28888584, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (19008294..19220699, complement)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107976930 Neighboring gene family with sequence similarity 171 member A1 Neighboring gene uncharacterized LOC134807134 Neighboring gene uncharacterized LOC129136251 Neighboring gene uncharacterized LOC129136250 Neighboring gene MINDY lysine 48 deubiquitinase 3 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
integrin alpha-8
Names
integrin, alpha 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    28676130..28888584 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_507671.8XP_507671.2  integrin alpha-8 isoform X1

    UniProtKB/TrEMBL
    A0A2I3T8Z7, A0A2J8K664, A0A6D2WBK6, H2Q1N7
    Related
    ENSPTRP00000085668.1
    Conserved Domains (2) summary
    smart00191
    Location:383437
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:483934
    Integrin_alpha2; Integrin alpha
  2. XM_054660790.2XP_054516765.1  integrin alpha-8 isoform X2

  3. XM_016962719.3XP_016818208.1  integrin alpha-8 isoform X3

    UniProtKB/TrEMBL
    H2Q1N7