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CREM cAMP responsive element modulator [ Pan troglodytes (chimpanzee) ]

Gene ID: 450400, updated on 3-Apr-2024

Summary

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Official Symbol
CREMprovided by VGNC
Official Full Name
cAMP responsive element modulatorprovided by VGNC
Primary source
VGNC:VGNC:12287
Locus tag
CK820_G0018754
See related
Ensembl:ENSPTRG00000002420
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (48083566..48171268)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (38445330..38533022)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807158 Neighboring gene cullin 2 Neighboring gene uncharacterized LOC134807160 Neighboring gene U7 small nuclear RNA Neighboring gene V-type proton ATPase subunit G 1-like Neighboring gene uncharacterized LOC104008146 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene cyclin Y

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of ATF4-CREB1 transcription factor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cAMP-responsive element modulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    48083566..48171268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001148504.7 → XP_001148504.1  cAMP-responsive element modulator isoform X9

    See identical proteins and their annotated locations for XP_001148504.1

    UniProtKB/TrEMBL
    A0A2I3RZS4, A0A2J8MMY9
    Conserved Domains (2) summary
    cd14690
    Location:243 → 297
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:68 → 105
    pKID; pKID domain

  2. XM_016963003.4 → XP_016818492.1  cAMP-responsive element modulator isoform X8

    UniProtKB/TrEMBL
    A0A2I3RZS4

  3. XM_016963001.4 → XP_016818490.1  cAMP-responsive element modulator isoform X7

    UniProtKB/TrEMBL
    A0A2I3RZS4, A0A2I3TPF2, A0A2J8MMZ4, A0A6D2X3U6
    Conserved Domains (2) summary
    cd14690
    Location:255 → 309
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:69 → 105
    pKID; pKID domain

  4. XM_009458261.5 → XP_009456536.1  cAMP-responsive element modulator isoform X10

    See identical proteins and their annotated locations for XP_009456536.1

    UniProtKB/TrEMBL
    A0A2I3RZS4, A0A2J8MMZ2, A0A803KGT4, K7CWW6
    Related
    ENSPTRP00000070239.1
    Conserved Domains (2) summary
    cd14690
    Location:243 → 297
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:68 → 105
    pKID; pKID domain

  5. XM_009458269.5 → XP_009456544.1  cAMP-responsive element modulator isoform X20

    See identical proteins and their annotated locations for XP_009456544.1

    UniProtKB/TrEMBL
    A0A2I3SF39, A0A2J8MMY4, A0A2J8MN22, A0A6D2WBN8
    Related
    ENSPTRP00000063351.1
    Conserved Domains (2) summary
    cd14690
    Location:180 → 234
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:68 → 105
    pKID; pKID domain

  6. XM_009458268.5 → XP_009456543.1  cAMP-responsive element modulator isoform X19

    See identical proteins and their annotated locations for XP_009456543.1

    UniProtKB/TrEMBL
    A0A2I3SF39, A0A2J8MMY4, A0A6D2WBN8
    Conserved Domains (2) summary
    cd14690
    Location:180 → 234
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:68 → 105
    pKID; pKID domain

  7. XM_063781636.1 → XP_063637706.1  cAMP-responsive element modulator isoform X30

  8. XM_063781623.1 → XP_063637693.1  cAMP-responsive element modulator isoform X5

    UniProtKB/TrEMBL
    A0A2I3TNK0, A0A2J8MN06, A0A6D2VXT5

  9. XM_063781624.1 → XP_063637694.1  cAMP-responsive element modulator isoform X6

  10. XM_063781635.1 → XP_063637705.1  cAMP-responsive element modulator isoform X29

  11. XM_016962997.4 → XP_016818486.1  cAMP-responsive element modulator isoform X2

    UniProtKB/TrEMBL
    A0A2I3S9Q7
    Related
    ENSPTRP00000073769.1
    Conserved Domains (2) summary
    cd14690
    Location:304 → 358
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  12. XM_009458275.5 → XP_009456550.1  cAMP-responsive element modulator isoform X1

    See identical proteins and their annotated locations for XP_009456550.1

    UniProtKB/TrEMBL
    A0A2I3S9Q7
    Conserved Domains (2) summary
    cd14690
    Location:304 → 358
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  13. XM_009458258.5 → XP_009456533.1  cAMP-responsive element modulator isoform X4

    UniProtKB/TrEMBL
    A0A2I3RZS4
    Conserved Domains (2) summary
    cd14690
    Location:292 → 346
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  14. XM_009458257.5 → XP_009456532.1  cAMP-responsive element modulator isoform X3

    See identical proteins and their annotated locations for XP_009456532.1

    UniProtKB/TrEMBL
    A0A2I3RZS4
    Conserved Domains (2) summary
    cd14690
    Location:292 → 346
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  15. XM_009458266.5 → XP_009456541.1  cAMP-responsive element modulator isoform X12

    UniProtKB/TrEMBL
    A0A2I3SF39, A0A2J8MMY4, A0A6D2WBN8
    Related
    ENSPTRP00000075107.1
    Conserved Domains (2) summary
    cd14690
    Location:229 → 283
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  16. XM_009458265.5 → XP_009456540.1  cAMP-responsive element modulator isoform X11

    See identical proteins and their annotated locations for XP_009456540.1

    UniProtKB/TrEMBL
    A0A2I3SF39, A0A2J8MMY4, A0A6D2WBN8
    Conserved Domains (2) summary
    cd14690
    Location:229 → 283
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  17. XM_063781627.1 → XP_063637697.1  cAMP-responsive element modulator isoform X14

  18. XM_063781626.1 → XP_063637696.1  cAMP-responsive element modulator isoform X13

  19. XM_063781630.1 → XP_063637700.1  cAMP-responsive element modulator isoform X22

  20. XM_063781629.1 → XP_063637699.1  cAMP-responsive element modulator isoform X21

    UniProtKB/TrEMBL
    A0A2I3T728, A0A2J8MMV0, A0A6D2XFR5

  21. XM_063781642.1 → XP_063637712.1  cAMP-responsive element modulator isoform X36

    UniProtKB/TrEMBL
    A0A2J8MMX3

  22. XM_063781633.1 → XP_063637703.1  cAMP-responsive element modulator isoform X26

  23. XM_063781631.1 → XP_063637701.1  cAMP-responsive element modulator isoform X25

  24. XM_024346304.3 → XP_024202072.1  cAMP-responsive element modulator isoform X36

    UniProtKB/TrEMBL
    A0A2J8MMX3
    Conserved Domains (1) summary
    cd14690
    Location:39 → 93
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  25. XM_063781638.1 → XP_063637708.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A2J8MMW2

  26. XM_024346301.3 → XP_024202069.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A2J8MMW2
    Conserved Domains (1) summary
    cd14690
    Location:39 → 93
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  27. XM_063781639.1 → XP_063637709.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A2J8MMW2

  28. XM_063781641.1 → XP_063637711.1  cAMP-responsive element modulator isoform X36

    UniProtKB/TrEMBL
    A0A2J8MMX3

  29. XM_016963005.4 → XP_016818494.1  cAMP-responsive element modulator isoform X9

    UniProtKB/TrEMBL
    A0A2I3RZS4, A0A2J8MMY9
    Conserved Domains (2) summary
    cd14690
    Location:243 → 297
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:68 → 105
    pKID; pKID domain

  30. XM_054660982.2 → XP_054516957.1  cAMP-responsive element modulator isoform X3

  31. XM_054660984.2 → XP_054516959.1  cAMP-responsive element modulator isoform X10

    UniProtKB/TrEMBL
    A0A2J8MMZ2, A0A803KGT4, K7CWW6

  32. XM_016962996.4 → XP_016818485.1  cAMP-responsive element modulator isoform X1

    UniProtKB/TrEMBL
    A0A2I3S9Q7
    Conserved Domains (2) summary
    cd14690
    Location:304 → 358
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:117 → 154
    pKID; pKID domain

  33. XM_001148567.7 → XP_001148567.1  cAMP-responsive element modulator isoform X15

    See identical proteins and their annotated locations for XP_001148567.1

    UniProtKB/TrEMBL
    A0A2I3SGK8, A0A2J8MMX6, A0A6D2Y8E6, A2T703
    Related
    ENSPTRP00000076126.1
    Conserved Domains (2) summary
    cd14690
    Location:213 → 267
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:38 → 75
    pKID; pKID domain

  34. XM_001147804.7 → XP_001147804.1  cAMP-responsive element modulator isoform X23

    See identical proteins and their annotated locations for XP_001147804.1

    UniProtKB/TrEMBL
    A0A2J8MMX2
    Conserved Domains (2) summary
    cd14690
    Location:150 → 204
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:38 → 75
    pKID; pKID domain

  35. XM_054660986.2 → XP_054516961.1  cAMP-responsive element modulator isoform X16

  36. XM_001149141.8 → XP_001149141.1  cAMP-responsive element modulator isoform X17

    See identical proteins and their annotated locations for XP_001149141.1

    UniProtKB/TrEMBL
    A0A2I3RZS4, A0A2J8MN11, A0A6D2XCR8, H2Q1T4
    Related
    ENSPTRP00000004130.7
    Conserved Domains (2) summary
    cd14690
    Location:188 → 242
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:13 → 50
    pKID; pKID domain

  37. XM_054660987.2 → XP_054516962.1  cAMP-responsive element modulator isoform X18

  38. XM_001147345.7 → XP_001147345.1  cAMP-responsive element modulator isoform X24

    See identical proteins and their annotated locations for XP_001147345.1

    UniProtKB/TrEMBL
    A0A2J8MMX0
    Conserved Domains (2) summary
    cd14690
    Location:125 → 179
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
    pfam02173
    Location:13 → 50
    pKID; pKID domain

  39. XM_063781634.1 → XP_063637704.1  cAMP-responsive element modulator isoform X26

  40. XM_063781632.1 → XP_063637702.1  cAMP-responsive element modulator isoform X25

  41. XM_063781637.1 → XP_063637707.1  cAMP-responsive element modulator isoform X30

  42. XM_003312521.6 → XP_003312569.1  cAMP-responsive element modulator isoform X34

    See identical proteins and their annotated locations for XP_003312569.1

    UniProtKB/TrEMBL
    A0A2J8MMZ6, K7AZY7
    Conserved Domains (1) summary
    cd14690
    Location:52 → 106
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  43. XM_003312528.6 → XP_003312576.1  cAMP-responsive element modulator isoform X33

    See identical proteins and their annotated locations for XP_003312576.1

    UniProtKB/TrEMBL
    A0A2J8MMW0
    Conserved Domains (1) summary
    cd14690
    Location:52 → 106
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  44. XM_001149485.6 → XP_001149485.1  cAMP-responsive element modulator isoform X28

    See identical proteins and their annotated locations for XP_001149485.1

    UniProtKB/TrEMBL
    A0A2J8MMW7, K7C2W7
    Conserved Domains (1) summary
    cd14690
    Location:64 → 118
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  45. XM_001147643.5 → XP_001147643.1  cAMP-responsive element modulator isoform X27

    See identical proteins and their annotated locations for XP_001147643.1

    UniProtKB/TrEMBL
    A0A2J8MMX7
    Conserved Domains (1) summary
    cd14690
    Location:64 → 118
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  46. XM_003312522.6 → XP_003312570.1  cAMP-responsive element modulator isoform X32

    See identical proteins and their annotated locations for XP_003312570.1

    UniProtKB/TrEMBL
    A0A2J8MMY7, A0A6D2VX35, K7BKC0
    Related
    ENSPTRP00000069974.1
    Conserved Domains (1) summary
    cd14690
    Location:56 → 110
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  47. XM_063781643.1 → XP_063637713.1  cAMP-responsive element modulator isoform X36

    UniProtKB/TrEMBL
    A0A2J8MMX3

  48. XM_024346299.3 → XP_024202067.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A2J8MMW2
    Conserved Domains (1) summary
    cd14690
    Location:39 → 93
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  49. XM_003312527.6 → XP_003312575.1  cAMP-responsive element modulator isoform X31

    See identical proteins and their annotated locations for XP_003312575.1

    UniProtKB/TrEMBL
    A0A2J8MN21, K7DAX8
    Conserved Domains (1) summary
    cd14690
    Location:56 → 110
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

  50. XM_024346300.3 → XP_024202068.1  cAMP-responsive element modulator isoform X35

    UniProtKB/TrEMBL
    A0A2J8MMW2
    Conserved Domains (1) summary
    cd14690
    Location:39 → 93
    bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
Nucleotide Protein
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