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NR4A1 nuclear receptor subfamily 4 group A member 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 451913, updated on 3-Apr-2024

Summary

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Official Symbol
NR4A1provided by VGNC
Official Full Name
nuclear receptor subfamily 4 group A member 1provided by VGNC
Primary source
VGNC:VGNC:5507
Locus tag
CK820_G0039616
See related
Ensembl:ENSPTRG00000004966
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (43814947..43851668, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (42488760..42510975, complement)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene olfactory receptor 7E24-like Neighboring gene small integral membrane protein 41 Neighboring gene autophagy related 101 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene U6 spliceosomal RNA Neighboring gene activin A receptor type 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear glucocorticoid receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to corticotropin-releasing hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4immunitygroup A member 1
Names
orphan nuclear receptor NR4A1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    43814947..43851668 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063786659.1 → XP_063642729.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X3

    UniProtKB/TrEMBL
    A0A2J8KDI6, A0A803KI99, K7D0Y5

  2. XM_009425363.4 → XP_009423638.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X6

    UniProtKB/TrEMBL
    A0A2J8KDJ3
    Conserved Domains (2) summary
    cl02596
    Location:337 → 364
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    cl11397
    Location:362 → 576
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  3. XM_009425361.4 → XP_009423636.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3RBZ8
    Conserved Domains (2) summary
    cd07348
    Location:433 → 670
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:337 → 411
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  4. XM_003313691.6 → XP_003313739.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RBZ8, A0A2J8KDI5, A0A6D2WB54, H2QZT3
    Related
    ENSPTRP00000039485.4
    Conserved Domains (2) summary
    cd07348
    Location:415 → 652
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:319 → 393
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  5. XM_003952188.6 → XP_003952237.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X5

    See identical proteins and their annotated locations for XP_003952237.1

    UniProtKB/TrEMBL
    A0A2J8KDI8, A0A803KLC9, G2HHP1, K7BQ21
    Conserved Domains (2) summary
    cd07348
    Location:361 → 598
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:265 → 339
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  6. XM_003313689.6 → XP_003313737.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X5

    See identical proteins and their annotated locations for XP_003313737.1

    UniProtKB/TrEMBL
    A0A2J8KDI8, A0A803KLC9, G2HHP1, K7BQ21
    Related
    ENSPTRP00000062138.1
    Conserved Domains (2) summary
    cd07348
    Location:361 → 598
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:265 → 339
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  7. XM_009425362.5 → XP_009423637.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X4

    UniProtKB/TrEMBL
    G2HHP1
    Conserved Domains (2) summary
    cd07348
    Location:365 → 602
    NR_LBD_NGFI-B; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
    cd06969
    Location:269 → 343
    NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

  8. XM_063786660.1 → XP_063642730.1  nuclear receptor subfamily 4immunitygroup A member 1 isoform X5

    UniProtKB/TrEMBL
    A0A2J8KDI8, A0A803KLC9, K7BQ21
Nucleotide Protein
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