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AXIN1 axin 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 453789, updated on 29-Mar-2024

Summary

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Official Symbol
AXIN1provided by VGNC
Official Full Name
axin 1provided by VGNC
Primary source
VGNC:VGNC:5679
Locus tag
CK820_G0054697
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (2627367..2699767, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (2627368..2699528, complement)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene Rho GDP dissociation inhibitor gamma Neighboring gene protein disulfide isomerase family A member 2 Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene post-GPI attachment to proteins 6 Neighboring gene large ribosomal subunit protein uL23-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables I-SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
axin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    2627367..2699767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024349594.3 → XP_024205362.1  axin-1 isoform X1

    UniProtKB/TrEMBL
    K7BX07
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:830 → 905
    DIX; DIX domain
    pfam08833
    Location:512 → 568
    Axin_b-cat_bind; Axin beta-catenin binding domain

  2. XM_024349598.3 → XP_024205366.1  axin-1 isoform X5

    UniProtKB/TrEMBL
    K7BX07
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:736 → 811
    DIX; DIX domain
    pfam08833
    Location:418 → 474
    Axin_b-cat_bind; Axin beta-catenin binding domain

  3. XM_024349595.3 → XP_024205363.1  axin-1 isoform X2

    UniProtKB/TrEMBL
    K7BX07
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:794 → 869
    DIX; DIX domain
    pfam08833
    Location:512 → 568
    Axin_b-cat_bind; Axin beta-catenin binding domain

  4. XM_024349596.3 → XP_024205364.1  axin-1 isoform X3

    UniProtKB/TrEMBL
    A0A2J8INH3, A0A803KL55, K7BX07, K7CI08
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:782 → 857
    DIX; DIX domain
    pfam08833
    Location:464 → 520
    Axin_b-cat_bind; Axin beta-catenin binding domain

  5. XM_024349597.3 → XP_024205365.1  axin-1 isoform X4

    UniProtKB/TrEMBL
    A0A2J8INH4, A0A803KKC8, K7BX07, K7D2P4
    Conserved Domains (4) summary
    cd08707
    Location:89 → 209
    RGS_Axin; Regulator of G protein signaling (RGS) domain found in the Axin protein
    cd11582
    Location:11 → 80
    Axin_TNKS_binding; Tankyrase binding N-terminal segment of axin
    pfam00778
    Location:746 → 821
    DIX; DIX domain
    pfam08833
    Location:464 → 520
    Axin_b-cat_bind; Axin beta-catenin binding domain
Nucleotide Protein
Heading Accession and Version

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