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NLRC5 NLR family CARD domain containing 5 [ Pan troglodytes (chimpanzee) ]

Gene ID: 454110, updated on 3-Apr-2024

Summary

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Official Symbol
NLRC5provided by VGNC
Official Full Name
NLR family CARD domain containing 5provided by VGNC
Primary source
VGNC:VGNC:57822
Locus tag
CK820_G0016610
See related
Ensembl:ENSPTRG00000048099
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
54
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 18 NC_072416.2 (54988020..55082359)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 16 NC_072414.1 (54988117..55082257)

Chromosome 18 - NC_072416.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U3 Neighboring gene cilia- and flagella-associated protein 69-like Neighboring gene cholesteryl ester transfer protein Neighboring gene copine 2 Neighboring gene proteasome activator subunit 3 interacting protein 1 Neighboring gene ring finger and SPRY domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of type I interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein NLRC5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072416.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    54988020..55082359
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054669366.2 → XP_054525341.1  protein NLRC5 isoform X14

  2. XM_016929879.4 → XP_016785368.1  protein NLRC5 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SLU3, A0A2J8MWB5, A0A663D843, K7AQT1
    Conserved Domains (4) summary
    sd00033
    Location:1524 → 1545
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1465 → 1495
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:222 → 383
    NACHT; NACHT domain
    cl26161
    Location:1522 → 1822
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_063797142.1 → XP_063653212.1  protein NLRC5 isoform X3

  4. XM_063797141.1 → XP_063653211.1  protein NLRC5 isoform X2

  5. XM_063797144.1 → XP_063653214.1  protein NLRC5 isoform X8

  6. XM_063797145.1 → XP_063653215.1  protein NLRC5 isoform X9

  7. XM_063797147.1 → XP_063653217.1  protein NLRC5 isoform X11

  8. XM_063797151.1 → XP_063653221.1  protein NLRC5 isoform X14

  9. XM_063797149.1 → XP_063653219.1  protein NLRC5 isoform X12

  10. XM_016929878.4 → XP_016785367.1  protein NLRC5 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SLU3, A0A2J8MWB5, A0A663D843, K7AQT1
    Conserved Domains (4) summary
    sd00033
    Location:1524 → 1545
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1465 → 1495
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:222 → 383
    NACHT; NACHT domain
    cl26161
    Location:1522 → 1822
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  11. XM_016929888.4 → XP_016785377.1  protein NLRC5 isoform X6

    UniProtKB/TrEMBL
    A0A2I3SLU3

  12. XM_016929883.4 → XP_016785372.1  protein NLRC5 isoform X3

    UniProtKB/TrEMBL
    A0A2I3SLU3

  13. XM_063797143.1 → XP_063653213.1  protein NLRC5 isoform X7

  14. XM_016929881.4 → XP_016785370.1  protein NLRC5 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SLU3

  15. XM_054669360.2 → XP_054525335.1  protein NLRC5 isoform X5

  16. XM_016929886.4 → XP_016785375.1  protein NLRC5 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SLU3, A0A2I3SST0, A0A2J8MWB4, A0A6D2XTP2
    Related
    ENSPTRP00000080103.1
    Conserved Domains (4) summary
    sd00033
    Location:1495 → 1516
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1436 → 1466
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:222 → 383
    NACHT; NACHT domain
    cl26161
    Location:1493 → 1793
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  17. XM_054669362.2 → XP_054525337.1  protein NLRC5 isoform X10

  18. XM_054669361.2 → XP_054525336.1  protein NLRC5 isoform X9

  19. XM_054669363.2 → XP_054525338.1  protein NLRC5 isoform X11

  20. XM_063797148.1 → XP_063653218.1  protein NLRC5 isoform X12

  21. XM_063797150.1 → XP_063653220.1  protein NLRC5 isoform X13

RNA

  1. XR_010152351.1 RNA Sequence

  2. XR_010152348.1 RNA Sequence

  3. XR_010152349.1 RNA Sequence

  4. XR_010152350.1 RNA Sequence

Nucleotide Protein
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