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SHC1 SHC adaptor protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 457351, updated on 29-Mar-2024

Summary

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Official Symbol
SHC1provided by VGNC
Official Full Name
SHC adaptor protein 1provided by VGNC
Primary source
VGNC:VGNC:10417
Locus tag
CK820_G0045184
See related
Ensembl:ENSPTRG00000001397
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See SHC1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (94218043..94230420)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (137119316..137131619, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene flavin adenine dinucleotide synthetase 1 Neighboring gene CDC28 protein kinase regulatory subunit 1B Neighboring gene dapper homolog 3 Neighboring gene pygopus family PHD finger 2 Neighboring gene PBX homeobox interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SHC-transforming protein 1
Names
SHC (Src homology 2 domain containing) transforming protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    94218043..94230420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009432874.3 → XP_009431149.1  SHC-transforming protein 1 isoform X7

    See identical proteins and their annotated locations for XP_009431149.1

    UniProtKB/TrEMBL
    A0A2I3R9Y2, A0A2J8Q331
    Conserved Domains (2) summary
    cd09925
    Location:371 → 474
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:36 → 207
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  2. XM_003308415.4 → XP_003308463.1  SHC-transforming protein 1 isoform X8

    See identical proteins and their annotated locations for XP_003308463.1

    UniProtKB/TrEMBL
    A0A2I3R9Y2, A0A2J8Q362
    Conserved Domains (2) summary
    cd09925
    Location:370 → 473
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:36 → 207
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  3. XM_016928174.3 → XP_016783663.1  SHC-transforming protein 1 isoform X9

    Conserved Domains (2) summary
    cd09925
    Location:353 → 456
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:36 → 189
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  4. XM_054686655.2 → XP_054542630.1  SHC-transforming protein 1 isoform X10

  5. XM_009432867.5 → XP_009431142.1  SHC-transforming protein 1 isoform X6

    See identical proteins and their annotated locations for XP_009431142.1

    Conserved Domains (2) summary
    cd09925
    Location:370 → 473
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:36 → 207
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  6. XM_513843.7 → XP_513843.3  SHC-transforming protein 1 isoform X3

    See identical proteins and their annotated locations for XP_513843.3

    UniProtKB/TrEMBL
    A0A2I3R9Y2, A0A2J8Q338
    Conserved Domains (2) summary
    cd09925
    Location:480 → 583
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 317
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  7. XM_009432852.4 → XP_009431127.1  SHC-transforming protein 1 isoform X2

    See identical proteins and their annotated locations for XP_009431127.1

    UniProtKB/TrEMBL
    A0A2I3R9Y2, A0A2J8Q333, A0A6D2WJ89, H2R8L2
    Related
    ENSPTRP00000051735.2
    Conserved Domains (2) summary
    cd09925
    Location:481 → 584
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 317
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  8. XM_009432864.5 → XP_009431139.1  SHC-transforming protein 1 isoform X4

    See identical proteins and their annotated locations for XP_009431139.1

    UniProtKB/TrEMBL
    A0A2I3R9Y2
    Conserved Domains (2) summary
    cd09925
    Location:463 → 566
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 299
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  9. XM_063812939.1 → XP_063669009.1  SHC-transforming protein 1 isoform X5

  10. XM_009432850.5 → XP_009431125.1  SHC-transforming protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3R9Y2
    Conserved Domains (2) summary
    cd09925
    Location:480 → 583
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 317
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

RNA

  1. XR_008548789.2 RNA Sequence

  2. XR_008548792.2 RNA Sequence

  3. XR_010157993.1 RNA Sequence

  4. XR_001709918.4 RNA Sequence

  5. XR_010157985.1 RNA Sequence

  6. XR_008548788.2 RNA Sequence

  7. XR_010157988.1 RNA Sequence

Nucleotide Protein
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