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cype cyclope [ Drosophila melanogaster (fruit fly) ]

Gene ID: 46040, updated on 14-Jun-2022

Summary

Official Symbol
cypeprovided by FlyBase
Official Full Name
cyclopeprovided by FlyBase
Primary source
FLYBASE:FBgn0015031
Locus tag
Dmel_CG14028
See related
AllianceGenome:FB:FBgn0015031
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH04604; CG14028; CG18323; Cox6c; COX6C; COXH; COXVIc; cyc; Cyc; Cype; Dmel\CG14028; l(2)03771; VIc
Summary
Predicted to enable cytochrome-c oxidase activity. Located in mitochondrion. Is expressed in several structures, including adult heart; gonad; imaginal disc; neuroblasts; and presumptive embryonic/larval central nervous system. Used to study cytochrome-c oxidase deficiency disease. Orthologous to human COX6C (cytochrome c oxidase subunit 6C). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See cype in Genome Data Viewer
Location:
25D6-25D6; 2-16 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.32 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5327227..5327969)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5327227..5327969)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nuclear receptor coactivator 6 Neighboring gene long non-coding RNA:CR44985 Neighboring gene uncharacterized protein Neighboring gene Turandot M

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
cyclope
Names
CG14028-PA
CG14028-PB
CG14028-PC
cype-PA
cype-PB
cype-PC
cytochrome c oxidase VIc
cytochrome c oxidase polypeptide VIc
cytochrome c oxidase subunit 6C
subunit VIc
NP_001245885.1
NP_001245886.1
NP_536787.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    5327227..5327969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258957.2NP_001245886.1  cyclope, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245886.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMS1
    Related
    FBpp0297878, FBtr0307035
    Conserved Domains (1) summary
    cd00927
    Location:877
    Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
  2. NM_080526.3NP_536787.1  cyclope, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_536787.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMS1
    Related
    FBpp0078707, FBtr0079072
    Conserved Domains (1) summary
    cd00927
    Location:877
    Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...
  3. NM_001258956.2NP_001245885.1  cyclope, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245885.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VMS1
    Related
    FBpp0297877, FBtr0307034
    Conserved Domains (1) summary
    cd00927
    Location:877
    Cyt_c_Oxidase_VIc; Cytochrome c oxidase subunit VIc. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...